Research Associate III, Viral Vector Production

Job Title: Research Associate I/II Viral Vector Production
Reports to: Process Development Scientist
Location: Berkeley California
Employment Type: Full Time onsite 5 days/week

FLSA Status: Exempt
Bonus/Equity: Eligible

About Azalea

Azalea Therapeutics is enabling precision genome engineering directly inside the body with an initial focus on creating cancer immunotherapiesin vivo. Azalea is pioneering a new way to turn a persons own T cells into a powerful cancer therapy directly inside the body. Instead of removing cells and manipulating them in a lab we use precision genome editing tools to engineer T cells where they already live. At the center of our approach are Enveloped Delivery Vehicles or EDVs. As highly selective couriers EDVs are designed to specifically locate T cells within the patient and deliver our genome engineering cargo. Once inside the cell the anti-cancer agent is inserted into a precise site in the genome ensuring safe and potent modifications to fortify the T cells against cancers.

Why this matters:

• We aim to make cell therapy faster and more accessible by avoiding complex manufacturing outside the body.
• Our platform is designed for precision so the right cells are safely programmed to effectively fight cancer.
• This technology has the potential to treat a wide range of cancers with a streamlined scalable process.

Our goal is simple:develop next-generation delivery technologies to bring genetic engineering and cell therapies to more patients.

The Opportunity

We are seeking a highly motivated and technically proficient Research Associate I/II to join our dynamic and growing team. Reporting to the Process Development Scientist this role will be central to Azaleas viral vector production pipeline directly impacting the delivery of our next-generation cell and genome therapies. As part of an innovative intellectually stimulating and fast-paced team the Research Associate I/II will execute the routine production and purification workflows that power our R&D engine.

The Research Associate I/II will have opportunities for rapid scientific and professional growth including the opportunity to specialize in advanced bioprocessing techniques and communicate findings within a collaborative team environment. The Research Associate I/II position requires on-site work 5 days/week at our world-class laboratory in Berkeley CA.

Key Responsibilities

• Execute routine production of viral vectors (e.g. AAV Lentivirus) to support platform development and therapeutic pipeline needs.
• Perform downstream purification processes specifically utilizing ultracentrifugation for vector concentration and polishing.
• Maintain mammalian cell lines and manage scale-up for production runs.
• Analyze production yields and quality data communicating results clearly within team meetings.
• Maintain detailed and organized records of production runs and experimental results
• Additional duties and responsibilities as required based on the needs of the company.

Qualifications

• Minimum Qualifications
  • BS/BA and/or MS/MA in bioengineering molecular biology cell biology or a related discipline with at least 1 year of laboratory research experience in an academic or industry setting.
  • Familiarity with ultracentrifugation techniques for the purification of biological particles.
  • Experience with mammalian cell culture (aseptic technique cell counting and maintenance).
  • Strong communication problem-solving organization and work ethic.
  • Familiarity with electronic laboratory notebooks (such as Benchling)
  • Ability to work both collaboratively and individually in a fast-paced production-oriented environment.
• Preferred Qualifications
  • Hands-on experience with standard unit operations (STR UFDF Chrom) for cell viral vector productions.
  • Experience with vector inventory management 5S or other lab-based logistics
  • Familiarity with vector characterization assays (e.g. qPCR/ddPCR for titration ELISA or Western blot).

What Success Looks Like (first 36 months)

• Develop hands-on proficiency with Azaleas viral vector production workflows including mammalian cell culture transfection and downstream purification using ultracentrifugation.
• Independently execute routine production runs with strong attention to sterility reproducibility and detailed documentation.
• Clearly analyze and communicate production results during team discussions while maintaining organized experimental records.
• Build familiarity with Azaleas platform technology and become a reliable contributor to the viral vector production pipeline.Gain hands on experience with scalable viral vector production approaches and associated processes.

Working Conditions / Physical Requirements (if/as applicable)

• Ability to sit and stand throughout the day to complete lab activities.

Compensation

• The expected salary range for this role based on the primary location for this position in California is $70000- $95000 per year. Offer amounts are determined by factors such as experience qualifications geographic location and other job-related factors permitted by law. Salary will be commensurate with experience qualifications training and market. Benefits include the potential for equity employer-sponsored 401k and competitive healthcare plans.

Azaleas Commitments

Equal Employment Opportunity (EEO): Azalea is an equal opportunity employer. We consider qualified applicants without regard to race color religion sex gender identity or expression sexual orientation national origin ancestry age disability medical condition genetic information marital status military or veteran status or any other characteristic protected by applicable law.

Reasonable Accommodation: We will provide reasonable accommodation to qualified individuals with disabilities and to individuals with sincerely held religious beliefs consistent with applicable law. To request accommodation email HR at .

Applicant Privacy: Azalea collects and uses applicant personal information for recruiting and employment purposes. If applicable Azalea will provide a California applicant privacy notice describing categories of information collected purposes retention and rights under the California Consumer Privacy Act (CCPA/CPRA).

Job Description Disclaimer: This job description may change at any time based on business needs. It is not a contract and does not create a promise of employment for any particular duration.

Notice to Recruiters/Staffing Agencies: Recruiters and staffing agencies should not contact Azalea Therapeutics through this page. We require that all Recruitment Vendors (e.g. search firms recruitment agencies and staffing companies) have a fully executed formal written agreement on file with Azalea prior to submitting candidates. Any resumes submitted through the website or directly by Recruitment Vendors will be considered unsolicited. Unsolicited vendor submissions do not constitute any actual or implied contract with Azalea and Azalea will not be responsible for any purported fees. For more information please contact our HR team at .

Information on Fraudulent Job Offers:Azalea is aware that some job seekers have received false employment offers or recruitment emails from individuals or organizations posing as Azalea. The individuals or organizations sending these false employment offers may send requests seeking to gain personal information items of value or monetary funds under the premise that doing so is required to further the recruitment process.

Azalea never requests passport details financial information items of value or money from job seekers for any reason as part of the recruitment process. Individuals who receive an offer of employment from Azalea are always required to go through a formal recruitment process which includes an interview with a member of Azaleas Human Resources recruitment team and the hiring manager.

Legitimate email communications from Azalea will also only use emails that end in @ from our core recruitment team. Fraudulent emails claiming to be sent by Azalea or Azalea employees may come from similar sounding emails with endings like @ or @ or even emails ending in common public domain addresses with endings like @ or @. There can also be instances of fraudulent communication that use the names and pictures of known company employees claiming to be sent from those employees or that even link out to fake websites that were created to look and feel like the real company website.

We are taking steps to investigate these fraudulent communications. If you feel that you have been a potential victim of an employment application scam please contact the Internet Crimes Complaint Center at. The Internet Crimes Complaint Center is an FBI entity that aggregates criminal events in order to analyze and prosecute numerous related scams.