Senior Scientist I, Biologics Purification

Join AbbVies Biologics Discovery Sciences group and make a tangible impact in advancing innovative biologic therapies. As a scientist specializing in Biologics Purification you will play a pivotal role in driving drug discovery collaborating within a dynamic team dedicated to supporting transformative science that improves patient lives worldwide. Your expertise will help deliver high-purity bispecific antibody-based biologic candidates with suitable purity/characteristics to support the advancement of vital in vitro (i.e. drug-like property assays binding cell-based assays etc.) and in vivo studies (i.e. efficacy non-GLP NHP PK DRF etc.). 

Key Responsibilities:

• Lead the purification of bispecific antibody biologics to support critical research assays and studies
• Champion the selection integration and application of advanced in silico tools to optimize complex protein separation
• Leverage Design of Experiments (DOE) with high throughput automation to evaluate and refine key process parameters to improve protein separation efficiency
• Design and execute advanced chromatography techniques and robust bioprocess development strategies to address production liabilities and enable process scalability. 
• Develop automated data capture workflows to enable AI/ML initiatives
• Collaborate with multidisciplinary teams translating molecular insights into functional results
• Stay current with emerging scientific literature to foster innovation and continuous improvement
• Present findings clearly to diverse audiences and document results with rigor

Qualifications :

• BS MS or PhD in Bioinformatics Biophysics Chemical Engineering or related field with typically 10 years (BS) 8 years (MS) or 0 years (PhD) of experience
• Deep proficiency in large-scale bioprocessing column chromatography and automated liquid handling platforms
• Proven expertise applying computational tools and predictive modelling to support bioprocess development for bispecific antibodies
• Experience with DOE methodologies and application to multivariate analysis
• Skilled in software systems and/or programming languages such as Unicorn Empower Python/CADET-Process GoSilico ASPEN Chromatography Matlab JMP Minitab Genedata Chromatics or SDMS platforms
• Experience with data extraction API ETL tools and LIMS platforms for data acquisition integration and management across multiple analytical platforms is a plus
• Strong understanding of molecular and post-translational attributes of biologics
• Exceptional analytical communication and presentation skills
• Collaborative spirit and dedication to scientific excellence

Why AbbVie Here we combine advanced science with our strong values cultivating a culture where curiosity is encouraged and meaningful contributions are recognized. Grow your career innovate boldly and make a difference in the lives of patients around the globe.

Ready to pioneer the future of biologics Apply and transform science into health at AbbVie.

Additional Information :

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: 

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future. 

• We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.

• This job is eligible to participate in our short-term incentive programs.

•  This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more visit  & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:

Work :

No

Employment Type :

Full-time