Sr. Director, Nonclinical Safety & Portfolio Strategy
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Job Location:
North Chicago, IL - USA
Monthly Salary:
Not Disclosed
Posted on:
12 hours ago
Vacancies:
1 Vacancy
Job Summary
Description:
AbbVies Development Biological Sciences department is seeking a Senior Director for its Portfolio Leadership Group. This pivotal leadership role will serve as a nonclinical safety representative for assigned molecules across AbbVies diverse portfolio. As a safety representative the Senior Director will be responsible for the overall strategy and execution of the nonclinical toxicology program collaborating cross-functionally with project leads providing data interpretation at various internal and external venues and authoring regulatory documents.
The ideal candidate will have 15 years of experience in the area of non-clinical safety within the pharmaceutical industry. He/she should have the experience and ability to develop drug candidates from discovery through marketing. This senior-level position is expected to have a high impact contributing scientific expertise in nonclinical safety assessment knowledge of industry best practices and pertinent regulatory guidelines and a vision of future enhancements in the field.
Responsibilities:
- Drive the strategic vision and direction for nonclinical safety influencing key R&D and portfolio decisions at the organizational level.
- Serve as an active member for multi-disciplinary project teams as a nonclinical safety functional area subject matter expert.
- Articulate and communicate non-clinical safety strategies and provide development plans for multiple drug modalities including but not limited to small molecules biologics ADCs and/or cell and gene therapies across various therapeutic areas including but not limited to oncology neuroscience and immunology.
- Participate in due diligence reviews of drug products to identify potential risks and provide recommendations for partnership or in-licensing.
- Author and submit regulatory documents (IBs INDs/CTAs NDAs/BLAs regulatory queries) and interact with regulatory agencies (US and ex-US) as needed.
- Generate impurity excipient and metabolite risk assessments as necessary during the life cycle of a drug candidate.
- Lead mentor and develop others as it pertains to drug development and the execution of the portfolio with an emphasis on the nonclinical aspects.
- Participation in pharmaceutical industry consortia related to nonclinical aspects of drug development.
Qualifications :
- PhD or DVM required.
- 15 years of relevant experience in pharmaceutical industry leading nonclinical safety programs.
- Experience authoring relevant regulatory documents and responding to requests from regulatory agencies.
- Deep expertise in a particular therapeutic area or modality (e.g. immunology gene therapy etc) is a benefit but not required.
- General awareness and understanding of drug metabolism and pharmacokinetics and its interplay with safety (e.g. MIST drug-drug interactions toxicokinetics anti-drug antibodies...) is a plus.
- Skilled in project/program management and leadership.
- General computer skills and knowledge of the Microsoft applications including but not limited to Microsoft Word Excel and PowerPoint and applying AI as appropriate and necessary.
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this postingbased on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more orless than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commissionincentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paidand may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:
No
Employment Type :
Full-time
Key Skills
- Business Development
- Marketing
- Pricing
- Analysis Skills
- Research Experience
- Project Management
- Research & Development
- Strategic Planning
- Financial Modeling
- Leadership Experience
- Management Consulting
- Analytics
About Company
AbbVie is a global biopharmaceutical company focused on creating medicines and solutions that put impact first for patients, communities, and our world. We aim to address complex health issues and enhance people's lives through our core therapeutic areas: immunology, oncology, neuro ... View more
