master's thesis project on Development and validation of a plasma extraction protocol

The Leibniz-IZW is an internationally recognised research institute belonging to the Leibniz Association. The institutes aim is to understand the adaptability of wild animals in an age of global change and to contribute to species conservation using scientifically sound methods. The Leibniz-IZW researches the distribution population dynamics and adaptations of wild animal species and investigates how they interact with pathogens environmental influences and humans. Research at the Leibniz-IZW is interdisciplinary and ranges from molecular biology studies to the analysis of landscapes and order to put its research into practice the institute works closely with stakeholders policy makers and conservationists.

For our Department of Reproduction Biology we are offering amasters thesis project on

Development and validation of a plasma extraction protocol for steroidomic and metabolomic analysis in wildlife species

Endocrinological research in endangered species can substantially support conservation programs by improving our understanding of their reproductive biology and physiological collaboration with Ghent University (Belgium) the Department of Reproduction Biology at the Leibniz Institute for Zoo and Wildlife Research has established a mass spectrometry based wildlife endocrine monitoring platform that enables comprehensive screening of a wide range of small molecules through the integration of two complementary approaches: steroidomics and polar to semi-polar metabolomics. Sample preparation represents a critical step in any analytical workflow and is highly dependent on the biological matrix as it aims to reduce background interference while enhancing the detectability of the compounds of interest. The objective of this project is therefore to develop and validate a robust plasma extraction protocol for both analytical methods in plasma samples of wildlife species.

Tasks:

Conducting systematic searches of scientific literature

Designing analytical experiments

Performing sample preparation extraction and UHPLC-HRMS analyses

Processing analyzing and interpreting analytical data

Writing and presenting experimental reports

Requirements:

Completed Bachelors degree in biotechnology biology or veterinary medicine

Experience or interest in mass spectrometry and/or analytical chemistry

Fluent in English (spoken and written)

The masters thesis can be started from 18th May 2026 on. Unfortunately we cannot offer any remuneration.

Enquiries or questions should be directed to the supervisor of the master thesis Tom Cools by email () or telephone.

We welcome applications regardless of gender origin sexual orientation and religion. Disabled persons will be given preferential consideration in case of equal suitability. The IZW lives the principles enshrined by the German Charta of Diversity (Charta der Vielfalt) has a diversity and inclusion strategy is Total-E-Quality certified promotes equality and actively supports a work-life balance. We promote diversity so please convince us with your quality and competence.

Are you interested:

Please apply exclusively via our recruiting portal (button Apply online) by 15 April 2026 and upload the following application documents there:

1) Short letter of motivation highlighting your skills for this position

2) Resume (maximum 3 pages)

3) Enrolment certifcate

4) Digital copies of relevant degree/s

We look forward to receiving your application!