Trainee Cardiovascular Research Institute
Share
Job Location:
New York City, NY - USA
Monthly Salary:
Not Disclosed
Posted on:
15 hours ago
Vacancies:
1 Vacancy
Job Summary
Details of Research Project: cell-cell communication (CCC) mediated by specific ligand-receptor interaction modulates several functions necessary for maintaining human health. Dysregulation in these interactions are observed in several disease conditions including heart failure chronic kidney disease cross-organ fibrosis. Current methods to quantify CCC are limited in terms of a) predicting the impact of these interactions of downstream functions in a cell and b) accounting for the impact on the overall phenotype. The goal of this project is to conduct a comprehensive benchmark of factors such changes in levels of ligands receptors and their downstream pathways in order to identify key ligand-receptor interactions associated with cross-organ fibrosis.
Goals/Outcomes of the Research Project: The goal of the project is to:
Develop a framework to compare CCC across organs
Evaluate the impact of ligand-receptor interactions in predicting their downstream pathway activation
Creation of a web-portal to host pre-computed cross-organ CCC interactions
Preparation of a final report and presentation
Responsibilities
The ideal candidate is fluent in Python and R programming languages. Experience in data pre-processing feature extraction methods supervised and unsupervised machine learning model evaluation and validation is essential. Previous knowledge of single-cell transcriptomics is desirable. Performs other related duties assigned.
Qualifications
- Education: High School Diploma or GED required; Associates or greater depending on department and role.
- Experience: None
Required Experience:
Intern
Key Skills
- Corporate Banking
- Access Control
- Civil Construction
- Infrastructure Development
- E-Commerce
- Data Analysis
About Company
Strength through Unity and Inclusion The Mount Sinai Health System is committed to fostering an environment where everyone can contribute to excellence. We share a common dedication to delivering outstanding patient care. When you join us, you become part of Mount Sinai’s unparalleled ... View more
