Purpose:
Drive the discovery of innovative therapies and treatments for obesity by designing and executing creative experimental strategies grounded in molecular pharmacology with emphasis on GPCR signaling trafficking and efficacy. Lead efforts to develop and optimize advanced in-vitro biochemical and cell-based assays to produce high-quality data with direct translational impact. Propel scientific innovation in GPCR pharmacology and obesity research by fostering robust cross-functional collaborations integrating multidisciplinary expertise and leveraging technological advancements to accelerate drug discovery.
Responsibilities:
- Demonstrate scientific initiative and creativity in GPCR pharmacology research and development activities.
- Independently develop and validate cell-based and biochemical assays to characterize GPCRs.
- Apply advanced techniques to assess biased agonism receptor internalization trafficking and signaling pathway modulation.
- Utilize high-throughput screening methods to identify novel GPCR modulators.
- Implement emerging technologies such as biosensor assays and CRISPR-based gene editing for assay development.
- Analyze and interpret complex data to draw conclusions and inform decision-making.
- Collaborate with cross-functional teams including chemists to support obesity research projects and SAR analyses.
- Maintain accurate and detailed records of experiments and results and adhere to corporate safety and compliance standards.
- Serve as primary author for scientific and regulatory reports and present findings to appropriate stakeholders.
Qualifications :
- Bachelors Degree or equivalent education and typically 10 years of experience Masters Degree or equivalent education and typically 8 years of experience PhD and no experience necessary.
- Degree in Pharmacology Cell Biology Biochemistry or related discipline (preferred) with relevant post graduate experience.
- Familiarity with quantitative assay development data analysis and interpretation in drug discovery.
- Experience in obesity metabolic or related disease area research is strongly preferred.
- Demonstrated ability to think independently troubleshoot and lead projects.
- Experience with laboratory automation and high-throughput screening is a plus.
- Demonstrated ability to thrive in a fast-paced cross-functional and dynamic environment function independently communicate effectively and collaborate closely with others.
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time ofthis posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic locationand we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:
Work :
No
Employment Type :
Full-time
Purpose:Drive the discovery of innovative therapies and treatments for obesity by designing and executing creative experimental strategies grounded in molecular pharmacology with emphasis on GPCR signaling trafficking and efficacy. Lead efforts to develop and optimize advanced in-vitro biochemical a...
Purpose:
Drive the discovery of innovative therapies and treatments for obesity by designing and executing creative experimental strategies grounded in molecular pharmacology with emphasis on GPCR signaling trafficking and efficacy. Lead efforts to develop and optimize advanced in-vitro biochemical and cell-based assays to produce high-quality data with direct translational impact. Propel scientific innovation in GPCR pharmacology and obesity research by fostering robust cross-functional collaborations integrating multidisciplinary expertise and leveraging technological advancements to accelerate drug discovery.
Responsibilities:
- Demonstrate scientific initiative and creativity in GPCR pharmacology research and development activities.
- Independently develop and validate cell-based and biochemical assays to characterize GPCRs.
- Apply advanced techniques to assess biased agonism receptor internalization trafficking and signaling pathway modulation.
- Utilize high-throughput screening methods to identify novel GPCR modulators.
- Implement emerging technologies such as biosensor assays and CRISPR-based gene editing for assay development.
- Analyze and interpret complex data to draw conclusions and inform decision-making.
- Collaborate with cross-functional teams including chemists to support obesity research projects and SAR analyses.
- Maintain accurate and detailed records of experiments and results and adhere to corporate safety and compliance standards.
- Serve as primary author for scientific and regulatory reports and present findings to appropriate stakeholders.
Qualifications :
- Bachelors Degree or equivalent education and typically 10 years of experience Masters Degree or equivalent education and typically 8 years of experience PhD and no experience necessary.
- Degree in Pharmacology Cell Biology Biochemistry or related discipline (preferred) with relevant post graduate experience.
- Familiarity with quantitative assay development data analysis and interpretation in drug discovery.
- Experience in obesity metabolic or related disease area research is strongly preferred.
- Demonstrated ability to think independently troubleshoot and lead projects.
- Experience with laboratory automation and high-throughput screening is a plus.
- Demonstrated ability to thrive in a fast-paced cross-functional and dynamic environment function independently communicate effectively and collaborate closely with others.
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time ofthis posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic locationand we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:
Work :
No
Employment Type :
Full-time
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