Non-Malignant Hematology in vitroin vivo Scientist1 year temporary contract

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The Position

The Position

Were currently looking for a lab-based scientist with a strong understanding of hematopoietic stem cell (HSC) biology / hematopoiesis to evaluate the efficacy safety and translatability of new therapies in non-malignant hematological disorders focusing on hemoglobinopathies. As part of a highly collaborative international team you will work alongside research associates and scientists developing medicines for the future.

This is a hands-on laboratory position. You will use cell culturebased in vitro models to characterize and validate therapeutic strategies for anemic disorders and support studies using preclinical animal models. This role requires strong expertise in cell culture assays and a range of in vitro techniques particularly flow cytometry along with prior experience in animal handling and experimentation.

These responsibilities capture a portion of what your work will look like:

• Contribute to early drug discovery projects by evaluating the efficacy and safety of novel therapeutic targets or compounds using cell culture assays and preclinical animal models.

• Work with cell lines primary cells and tissues including patient-derived material performing genetic manipulation assays ex vivo differentiation cultures and molecular assays (e.g. multicolor flow cytometry qPCR western blotting).

• Work with transgenic mouse models including handling tissue collection and processing

• Independently design execute and interpret complex preclinical studies; and guide associates as needed.

• Analyze data using robust statistical methods maintain detailed documentation and effectively communicate findings to the research team

• Collaborate with team members share responsibilities maintain a clean lab and foster a positive work environment.

Who You Are

You are genuinely driven curious about science and thrive in an energetic collaborative team. You seek opportunities to explore your interests across teams and regions and working in a multicultural environment motivates you.

• PhD in Life Sciences (e.g. cellular/molecular biology pharmacology immunology hematology) is a required

• Strong theoretical and technical background in HSC biology and hematopoiesis proven by a track record of publications and collaborations is a must-have.

• Extensive experience in cell culture and in vitro molecular assays with a specific must-have expertise in multicolor flow cytometry.

• Authorization to conduct animal experimentation (e.g. active LTK1 FELASA or equivalent) and prior experience working with rodents are must-have requirements.

• A strong can-do attitude being highly organized committed to meticulous record-keeping and adaptable to a fast-paced environment are essential.

• Fluency in English with strong presentation and communication skills is required.

• Relevant industrial experience is preferred but not mandatory

Ready to take the next step Wed love to hear from you. Apply now to explore this exciting opportunity!

Who we are

A healthier future drives us to innovate. Together more than 100000 employees across the globe are dedicated to advance science ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities foster creativity and keep our ambitions high so we can deliver life-changing healthcare solutions that make a global impact.

Lets build a healthier future together.

Roche is an Equal Opportunity Employer.