Senior Director, Translational Research Cell Therapy

Working with Us
Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here uniquely interesting work happens every day in every department. From optimizing a production line to the latest breakthroughs in cell therapy this is work that transforms the lives of patients and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits services and programs that provide our employees with the resources to pursue their goals both at work and in their personal lives. Read more: Cell Therapy Thematic Research Center is one of BMSs differentiated research platforms delivering innovative therapies to patients. Our mission is to drive leadership in the use of cellular therapies to harness the power of the immune system in treating hematologic malignancies solid cancers and autoimmune disease. More specifically our discovery and translational scientists are focused on developing next-generation engineered cell-based therapies. The team is committed to discovering and developing transformative therapies that harness the power of the immune system to improve patient outcomes.

Position Summary

The Senior Director Translational Research Cellular Therapy will provide scientific and people leadership for translational strategy execution and correlative analysis across Bristol Myers Squibbs cellular therapy portfolio. This role is responsible for shaping and delivering integrated translational and biomarker strategies that enable development decisions regulatory success and lifecycle management of cell therapy assets across hematologic malignancies and where applicable solid tumors autoimmunity and neuro-inflammation.

The successful candidate will lead and mentor a team of translational scientists and serve as a senior scientific leader on crossfunctional teams partnering closely with Clinical Development Discovery CMC Regulatory Computational Biology and external collaborators. This individual will be accountable for the quality rigor and impact of translational data packages supporting key development decisions global regulatory submissions and health authority interactions.

This position sits in the Translational Research organization within the Cellular Therapy Thematic Research Center (CT TRC) and plays a critical role in bridging discovery early and late clinical development and enterpriselevel decision making for cellular therapies.

Position Responsibilities

In the role as a Senior Director within Translational Research the ideal candidate will:

Scientific & Translational Leadership

• Define lead and execute endtoend translational and biomarker strategies for cellular therapy programs from firstinhuman through registration and lifecycle management.

• Integrate clinical translational and mechanistic data to generate actionable insights on mechanism of action resistance durability of response safety efficacy as well as potential patient selection and differentiation.

• Drive hypothesis-based translational research and response modeling leveraging multi-modal datasets ML/AI and innovative computational approaches to support forward and reverse translation.

• Ensure translational deliverables meet high scientific operational and regulatory standards and are aligned with program and portfolio objectives.

People & Team Leadership

• Build lead and develop a highperforming team of translational scientists through thoughtful recruitment coaching and ongoing feedback.

• Foster a culture of scientific rigor collaboration accountability and continuous learning.

• Guide team members in critical data analysis interpretation communication and prioritization to support timely and impactful decision making.

CrossFunctional & Matrix Leadership

• Serve as the senior translational representative on global crossfunctional leadership teams and internal governance forums.

• Partner effectively with Clinical Development Regulatory Affairs Discovery Biology Computational Biology CMC and Commercial colleagues to align translational strategies with clinical and business objectives.

• Communicate key translational insights risks impact and milestones clearly to diverse external and internal audiences including senior leadership.

Regulatory & External Engagement

• Provide translational leadership and accountability for regulatory submissions (e.g. INDs BLAs/MAAs) responses to health authority questions and regulatory interactions.

• Accountable for content of translational sections of clinical protocols investigator brochures regulatory documents and scientific publications.

• Establish and manage productive external collaborations with academic partners CROs and key opinion leaders to advance enterprise objectives.

Innovation & Ways of Working

• Champion innovative approaches to translational science including responsible application of AI LLM tools advanced analytics and new biomarker technologies to scale impact and efficiency.

• Maintain deep awareness of the external scientific and clinical landscape to inform strategy differentiation and future investment.

Experience

Basic Qualifications

• Bachelors Degree

  • 15 years of academic and / or industry experience

Or

• Masters Degree

  • 12 years of academic and / or industry experience

Or

• Ph.D. or equivalent advanced degree in the Life Sciences

  • 10 years of academic and / or industry experience

• 8 years of leadership experience

Preferred Qualifications

• Ph.D. M.D. or equivalent advanced degree in immunology oncology cell biology or a related discipline.

• 12 years of relevant experience in translational research and/or clinical drug development with significant experience in cellular therapies.

• Demonstrated success leading translational or biomarker strategies for clinicalstage programs including experience supporting regulatory filings and interactions.

• Proven people leadership experience including building mentoring and managing scientific teams in a matrixed environment.

• Deep expertise in immunology immuneoncology tumor biology and/or hematologic malignancies.

• Strong background in biomarker discovery and development including assay development/validation and clinical application.

• Experience integrating computational genomic and multimodal data to inform translational hypotheses development decisions and reverse translational application to discovery programs.

• Track record of scientific publications and impactful contributions to development programs.

• Excellent verbal and written communication skills with the ability to distill complex scientific concepts for diverse audiences.

• Demonstrated ability to operate effectively across discovery development and enterprise contexts balancing scientific ambition with pragmatic execution.

Leadership Competencies

• Strategic scientific thinking with a strong bias toward action and decision support

• Collaborative inclusive leadership style with a passion for developing talent

• Comfort operating in ambiguity while maintaining urgency and rigor

• Credibility as a scientific thought partner internally and externally

#LI-Onsite

If you come across a role that intrigues you but doesnt perfectly line up with your resume we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job such as required skills where the job is performed the employees work schedule job-related knowledge and experience. Final individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits please visit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

• Health Coverage: Medical pharmacy dental and vision care.

• Wellbeing Support: Programs such as BMS Well-Being Account BMS Living Life Better and Employee Assistance Programs (EAP).

• Financial Well-being and Protection: 401(k) plan short- and long-term disability life insurance accident insurance supplemental health insurance business travel protection personal liability protection identity theft benefit legal support and survivor support.

Work-life benefits include:

Paid Time Off

• US Exempt Employees: flexible time off (unlimited with manager approval 11 paid national holidays (not applicable to employees in Phoenix AZ Puerto Rico or Rayzebio employees)

• Phoenix AZ Puerto Rico and Rayzebio Exempt Non-Exempt Hourly Employees: 160 hours annual paid vacation for new hires with manager approval 11 national holidays and 3 optional holidays

Based on eligibility* additional time off for employees may include unlimited paid sick time up to 2 paid volunteer days per year summer hours flexibility leaves of absence for medical personal parental caregiver bereavement and military needs and an annual Global Shutdown between Christmas and New Years Day.

All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

*Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours depending on the nature of their work and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors leased workers and other service providers are not eligible to participate in the program.

Uniquely Interesting Work Life-changing Careers
With a single vision as inspiring as Transforming patients lives through science every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture promoting global participation in clinical trials while our shared values of passion innovation urgency accountability inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential site-by-design field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles onsite presence is considered an essential job function and is critical to collaboration innovation productivity and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application or in any part of the recruitment process direct your inquiries to . Visit to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider for employment qualified applicants with arrest and conviction records pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position please visit this page for important additional information: Protection

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