Senior Scientist, Oncology Research

Cambridge - UK

Monthly Salary: Not Disclosed

Posted on: Yesterday

Vacancies: 1 Vacancy

Job Summary

Job Title: Senior Scientist Oncology Research

Location: Cambridge (Discovery Centre) UK

Salary: Competitive Excellent Employee Benefits!

Introduction to the Role:

At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial thinking big and working together to make the impossible a reality.Werepassionate about the potential of science to address the unmet needs of patients around the world. We commit to those areas where we believe we can really change the course of medicine and bring bignew ideasto life.

Are you ready to work on one of the most exciting pipelines in the Oncology industry

AstraZenecas vision in Oncology is to push the boundaries of science to change the practice of medicine transform the lives of patients living with cancer and toultimately eliminatecancer as a cause of death.

About the Role:

We areseekingahighly motivatedSenior Scientistwith deep scientific and technicalexpertisespanning both adaptiveand innateimmune cell biologywitha track recordof scientific excellence to joinImmune Cell Engagers Discoveryteamin Cambridge UKfor afixed-term (12-month)position. As a Senior Scientistyou will be a key member of a team focused on supporting immune-oncology projects through the drug discovery process. You will bring your theoretical and practicalexpertisein immunology toestablishassay systems and deliver datasets that will have direct impact onimmune-oncology research projects.

Main Duties and Responsibilities:

Working in this laboratory-based position within the Immune Cell Engagers Discoverygroupyou will develop design conduct and analysein-vitroand/orex-vivoexperiments to assess the function of our candidate drugs and helpusto dissect the mechanism of action of novel therapeutics targeting the immune system for cancer therapy. You will also review emerging literature and internal data to help inidentifyingnew potential targets and contribute to target validation activities.

A strong foundationin immunology / immuno-oncology andan in-depthtechnicalexpertisefor the analysis of immune function and phenotype is essential for this role. As a highlyorganisedandself-motivated individual with a strong lab/practical background you will stay up to date with relevant technical and intellectual scientificexpertisein tumour immunology and have a genuine passion for this field of research!

Essential Requirements

A PhD or equivalent experience in immunology/Immuno-oncology/cancer biology.

Extensive background in immunology and/orimmuno-oncology.

Experience of a range ofin-vitroandex-vivotechnicalskills for the analysis of human immune cell functionsviamultiparameter flow cytometry ELISA/multiplex assaysELISPOTprimary immune cellisolation andco-culturescell killing assays(likeTDCC ADCC CDC ADCP)TILsisolation andphenotyping.

Molecularbiology skills includinggene expression analysis and stable cell line generation.

Working experience with immune cellassaysand/orcharacterization is highly desirable.

Strong interpersonal influencing negotiating and collaboration skills together with evidence of having used theseskillsto support problem solving andindelivering theprojects ina collaborative environment.

Depth of understanding andstrongenthusiasm for immunology and immuno-oncology.

Proventrack recordofscientific accomplishmentsasevidentfrom publications/patents.

Data processing statisticalanalysisand interpretation.

Experienceinpreparing written scientific reports (e.g.manuscripts) and oral presentations (e.g.slides posters).

Ability to record protocols and experimentsin a timely mannerandmaintainan excellent electronicnotebook(eLNB).

Desirable Requirements

We encourage applications from candidates who haveexperience in the evaluation of immunecellfunctionsandindevelopingand deployingcomplex immunological assaysto understand the MOA of novel therapeutics.

Expertisein fieldsof T-cell engagersT cell exhaustion tumour myeloid and/or NK biology.

Experienceinvisualizing/quantifyinghigh content multi-parameter flowcytometrydata/transcriptomic datasets.

Candidates who candemonstrateproficiencyinleveragingAI technologies including machine learning data analysis and algorithm development to enhance research outcomes alongside strongproblem solvingskills to enable integration of these tools into scientific workflows are strongly preferred.

Prior experience with spectral flow cytometry.

Working experience with 3Dcell culture.

Experienceinworking with patient-derived tumours/TILs

Knowledge of the drug discovery process.

So whats next

Are you already imagining yourself joining our team Good because we cant wait to hear from you!

Where can I find out more

Our Social Media

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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds with as wide a range of perspectives as possible and harnessing industry-leading skills. We believe that the more inclusive we are the better our work will be. We encourage and consider applications to join our team from all qualified candidates regardless of their characteristics. We comply with all applicable laws and regulations on inclusivity in employment (and recruitment) as well as work authorization and employment eligibility verification requirements.

Date Posted

19-Feb-2026

Closing Date

07-Mar-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion starting with our recruitment process. We welcome and consider applications from all qualified candidates regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations please complete the section in the application form.

Required Experience:

Senior IC

Job Title: Senior Scientist Oncology ResearchLocation: Cambridge (Discovery Centre) UKSalary: Competitive Excellent Employee Benefits! Introduction to the Role:At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial thinking big and working together to ma...