Small-Scale Purification Scientist

Work Schedule

Environmental Conditions

Job Description

About the Role

The Small-Scale Purification Scientist is a hands-on technical contributor in the Bioprocess Design Center (BDC) responsible for designing executing and documenting downstream purification experiments that generate high-quality technical evidence for Thermo Fisher Scientifics single-use purification technologies.

This role operates at the intersection of experimental execution and systems-level process understanding. The successful candidate will independently own small-scale downstream studies translate experimental outcomes into actionable insights and support integrated end-to-end workflow development across upstream harvest and downstream unit operations. Familiarity with Thermo Fisher Scientifics single-use downstream purification equipment consumables and workflow architectures is highly valued and will enable rapid execution within BDC laboratory and customer-facing environments.

Key Responsibilities

Experimental Design & Execution

• Execute purification resin design studies for internal and external customers using Thermo Fishers brand resins.
• Independently design and execute small-scale downstream purification experiments spanning capture intermediate and polishing operations.
• Develop experimental plans aligned to defined technical objectives including appropriate controls success criteria and data quality expectations.
• Execute chromatography and filtration processes (e.g. column screening process optimization UF/DF) with a focus on Thermo Fisher single-use chromatography and centrifugation systems.
• Troubleshoot experimental issues and drive resolution with minimal supervision.

Systems & Workflow Awareness

• Apply systems-level thinking to understand how downstream purification integrates with upstream processes automation analytics and overall workflow design.
• Support evaluation of single-use purification technologies process configurations and operating strategies.
• Identify operational risks constraints and improvement opportunities during experimental execution.

Data Analysis & Documentation

• Analyze experimental data identify trends and draw scientifically defensible conclusions.
• Author protocols technical reports summaries and SOPs suitable for internal use and customer-facing communication.
• Maintain complete accurate laboratory notebooks and records in accordance with internal data integrity and IP standards.

Collaboration & Communication

• Support customer visits technical demonstrations and internal reviews by clearly articulating experimental intent methods and results.
• Communicate progress risks and outcomes effectively to both technical and non-technical stakeholders.

Laboratory Operations & Compliance

• Maintain a safe compliant and well-organized laboratory environment.
• Follow applicable safety quality and training requirements (e.g. GLP ISO internal EHS standards).
• Contribute to continuous improvement of downstream laboratory workflows and experimental practices.
• Support preparation of bills of materials and logistical needs for BDC projects and customer activities.

Qualifications

Education

• B.S. in Chemical Engineering Biochemistry Biotechnology Bioengineering or related field with 35 years of relevant downstream experience
• M.S. with 23 years of relevant experience
• Equivalent combinations of education and experience will be considered

Experience & Skills

• Hands-on experience with downstream purification and bioprocessing workflows
• Familiarity with selection setup and operation of single-use chromatography columns flow kits and UF/DF systems.
• Experience designing and executing controlled experiments; DoE experience preferred
• Strong data analysis documentation and technical writing skills
• Proficiency with standard data analysis and reporting tools (e.g. Excel PowerPoint)

Preferred Attributes

• Demonstrated ability to work independently in a fast-paced matrixed environment
• Strong problem-solving skills and attention to detail
• Ability to translate experimental data into practical workflow-relevant insights
• Comfort operating in environments with evolving priorities and requirements
• Collaborative customer-centric mindset

Physical Requirements

• Ability to work in a laboratory environment and handle light to moderate lifting (up to 50 lbs)
• Standing and walking for extended periods during experimental execution
• Manual dexterity to operate laboratory equipment and instrumentation

Why Join the Bioprocess Design Center

The BDC is where Thermo Fisher technologies are stress-tested validated and translated into real-world customer solutions. This role offers hands-on exposure to cutting-edge single-use purification systems ownership of meaningful technical work and the opportunity to contribute data that directly shapes customer confidence and adoption.

Compensation and Benefits

This position may also be eligible to receive a variable annual bonus based on company team and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on which includes:

• A choice of national medical and dental plans and a national vision plan including health incentive programs

• Employee assistance and family support programs including commuter benefits and tuition reimbursement

• At least 120 hours paid time off (PTO) 10 paid holidays annually paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave) accident and life insurance and short- and long-term disability in accordance with company policy

• Retirement and savings programs such as our competitive 401(k) U.S. retirement savings plan

• Employees Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits please visit: Experience:

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