Application Specialist in Cryo-Correlative Light and Electron Microscopy (cryo-CLEM) – EMBL Imaging Centre

Since its inauguration in 2021 the EMBL Imaging Centre (IC) has rapidly established itself as a world-leading user facility for cutting-edge light and electron microscopy (LM and EM). Its core mission is to provide researchers across EMBLs member states with open access to the most advanced imaging technologies enabling investigations that span molecular cellular and organismal scales. By offering high-end instrumentation as well as completely new developments as reliable expert-supported services the EMBL Imaging Centre plays a central role in advancing pioneering life science research positioning itself at the forefront of integrated life science infrastructure in Europe (for more information see the EMBL Imaging Centre now fully operational and continuing to grow in scope we are seeking new team members to join our team.

The Cryo-Electron Microscopy Team led by Simone Mattei at the EMBL IC is looking for expert imaging professionals with a strong motivation for highest-level user service provision. Areas of expertise may include correlative light and electron microscopy (CLEM) cryo-super-resolution light microscopy and cryo-focused ion beam milling/scanning electron microscopy.

Your role

The successful applicants will be part of an international highly collaborative team comprising microscopy engineers application specialists image analysts and project managers having the mission of highest-level user service provision and workflow development.

Key responsibilities include:

• Lead the development and integration of cryo-super-resolution platforms to establish robust service-ready cryo-CLEM workflows aligned with EMBL IC service mission
• Coordinate method and workflow development in close collaboration with EMBL IC engineers application specialists instrument developers and industrial partners.
• Provide end-to-end user support for correlative microscopy projects including sample preparation experimental planning hands-on assistance during imaging and data acquisition troubleshooting and guidance on data management and analysis.
• Setting-up testing and ensuring smooth running of the instrumentation interacting with service engineers and helping to maintain and develop the local infrastructure.
• Developing expertise across the technology and service portfolio of the cryo-electron microscopy team and staying up to date with the latest developments in the correlative light and electron microscopy field.
• Training of EMBL IC users as well as other imaging experts in instrument usage and newly developed workflows.
• Contributing to microscopy courses and workshops for the IC users and imaging community in general.

You have

• PhD in the life sciences physics engineering or related disciplines.
• Proven experience in correlative (cryo-)light and electron microscopy techniques related image analysis and their application to biological questions.
• Experience in development of custom built light microscopy setups and their deployment on biological samples.
• Curiosity and strong motivation to become an imaging expert for a broad technology spectrum.
• Strong motivation to support and train users.
• Excellent communication and organisation skills.
• Ability to work creatively rigorously and independently.
• Fluency in English.

You may also have

• Experience in user support in an imaging facility.

• Experience in organising and running courses.

Contract length: 3 years (fixed term)

Salary: Grade 6 monthly salary from EUR 4.580 EUR (after tax and before 12.05% EMBL social security deductions) plus other paid benefits

Application process

In your online application please submit a cover letter a CV and contact details of 3 referees. Please elaborate in your cover letter how your experience and background would support the Imaging Centres mission of providing and expanding our cutting-edge imaging services .

We will conduct two rounds of interviews: First online after the closing date followed by onsite interviews in the week of 20 April 2026.

Further information about the position can be obtained from Simone Mattei ().

Why join us

EMBL is curiosity-driven community-oriented and international. As an inclusive equal opportunity employer we believe that diversity enables us to collaborate more effectively and be innovative in our approaches. We are therefore committed to creating an inclusive and flexible culture - one where everyone can realise their full potential and make a positive contribution to our organisation.

We encourage applications from individuals who can complement our existing team we believe that success is built on having teams whose backgrounds and personal experiences reflect the diversity of the populations that our science serves. We actively encourage applications from all genders and cultures ethnic groups and all demographics to help us avoid perpetuating biases and oversights at this transformational point in our people strategy.

Enjoy lots of benefits:

• Financial incentives:Salary free of income tax Monthly family child and non-resident allowances annual salary review pension scheme death benefit long-term care accident-at-work and unemployment insurances

• Flexible working arrangements

• Private medical insurancefor you and your immediate family (including all prescriptions and generous dental & optical cover)

• Generous time off:30 days annual leave per year in addition to public holidays

• Relocation packageincluding installation grant (if applicable)

• Campus life:Free shuttle bus (Heidelberg) library subsidised on-site cafeteria casual dress code extensive sports and social club activities (on campus and remotely)

• Family benefits: Kindergarten (Heidelberg) 10 days of child sick leave generous paid maternity/parental leave and monthly family & child allowances

• Benefits for international newcomers:Visa exemption education grant for private schooling financial support to travel back to your home country every second year and a monthly non-resident allowance.

• For detailed information please visit our employee benefits page here

What else you need to know

• International applicants: We recruit internationally and successful candidates are offered visa exemptions. Visit our International Applicants page to find out more.

• EMBL is a signatory of DORA. Find out how we apply DORA principles to our recruitment and performance assessment processes here.

• Diversity and inclusion: At EMBL we believe that diverse teams drive innovation and scientific excellence. We encourage applications from candidates of all genders identities nationalities and/or any other diverse backgrounds.

• How to apply: To apply please submit a cover letter and a CV through our online system. Applications will close at 23:59 CET on the date shown below. We aim to provide a response within two weeks after the closing date.

Closing Date