Intern-Clinical Immunology

AskBio Inc. a wholly owned and independently operated subsidiary of Bayer AG is a fully integrated gene therapy company dedicated to developing life-saving medicines and changing lives. The company maintains a portfolio of clinical programs across a range of neuromuscular central nervous system cardiovascular and metabolic disease indications with a clinical-stage pipeline that includes investigational therapeutics for congestive heart failure limb-girdle muscular dystrophy multiple system atrophy Parkinsons disease and Pompe disease. AskBios gene therapy platform includes Pro10 an industry-leading proprietary cell line manufacturing process and an extensive array of capsids and promoters. With global headquarters in Research Triangle Park North Carolina and European headquarters in Edinburgh Scotland the company has generated hundreds of proprietary capsids and promoters several of which have entered pre-clinical and clinical testing.

Our vision: Pioneering science to create transformative molecular medicines.

Our mission: Lead innovative science and drive clinical outcomes to transform peoples lives.

Our principles:

• Advance innovative science by pushing boundaries.

• Bring transformative therapeutics to patients in need.

• Provide an environment for employees to reach their fullest potential.

Our values:

• Be a Pioneer. We are not afraid of the impossible and to innovate to make gene therapies accessible to those in need.

• Cultivate Collaboration. Strive to be the best teammate actively listen openly communicate and embrace diverse points of view.

• Embrace Responsibility. We are humbled by the enormity of our hold a relentless commitment to advance science and clinical outcomes for our patients families and caregivers.

• Raise the Bar. Continuously drive improvements and efficiencies. Seek and provide constructive feedback. Have a bias for learning and action.

• Act with Uncompromising Integrity. Be honest transparent and committed to doing whats right in every situation. Make clear commitments and follow through.

Position Summary

The intern will contribute to key projects within the Clinical Immunology team focusing on improving consistency and supporting immunological research. This role offers hands-on experience with laboratory techniques and data analysis as well as exposure to cross-functional collaboration.

The intern will focus on the following projects

Project 1: Compare the parameters and performance of analytical lab instruments (e.g. fluorescent cell counter) between two lab locations to ensure alignment within an acceptable range for downstream analytical T cell assay testing.

Project 2: Perform cytokine testing on supernatant samples collected from T cell assays to support immunological understanding of AAV.

The intern will receive comprehensive training on both cell counting and supernatant testing before executing these projects. At the end of the program the intern will present findings and recommendations to the Clinical Immunology team.

This work will help standardize processes across sites and provide valuable insights into immune responses contributing to the advancement of clinical programs.

The intern will report to a Scientist on the Clinical Immunology team. This position is based at the RTP site.

Job Responsibilities

• Learn about adeno-associated virus (AAV) gene therapy and understand the role of Clinical Immunology in the AAV pipeline.

• Partner with analysts and scientists in the Clinical Immunology group to gain hands-on experience in immunological assays and data interpretation.

• Observe and evaluate clinical program results including immune response data related to AAV therapies.

• Participate in laboratory activities including MSD assays and attend Clinical Immunology team meetings to understand workflows and decision-making processes.

• Assist with supernatant and cell counter testing

• Maintain accurate records of experimental procedures and results in compliance under Good Clinical Laboratory Practices (GCLP)

• Communicate effectively with team members regarding project progress and findings.

• Present summarized findings and observations to the Clinical Immunology team at the conclusion of the internship

Minimum Requirements

• Must be pursuing a Bachelors degree in Biology Biomedical Engineering Molecular Biology Pre-Health

• Must be at least a Sophomore in university at the time of your application

• Strong sense of accountability ability to prioritize multiple tasks and curiosity for science

• Excellent organizational and communication skills and attention to detail

• Flexible and willing to support a variety of tasks for the Clinical Immunology team

• Proactive and solution-driven mindset

• Strong sense of accountability and ability to prioritize multiple tasks

• Excellent organizational skills and attention to detail

• Available to work full-time at the office during the summer months (May-August) at an AskBio office

Preferred Education Experience and Skills

• Prior internship work or volunteer/extracurricular experience

• Prior experience working in a lab environment that involves skills in pipetting and dilutions

AskBio Inc. (AskBio) is an Equal Opportunity Employer and does not discriminate against any employee or applicant for employment because of race color religion gender sexual orientation gender identity national origin age disability veteran status or any other protected status prohibited under Federal State or local laws. All employment decisions are based on valid jobrelated requirements. If you are a qualified individual with a disability or a disabled veteran and are unable or limited in your ability to use or access our website you may request a reasonable accommodation to express interest in a specific opening by calling us at or sending us an email at .

Agencies: Please do not contact any employee at AskBio about this requisition. Any resume submitted by a recruitment agency to any employee at AskBio through any medium will be deemed the sole property of AskBio unless the agency was engaged by AskBio Talent Acquisition team to recruit for that position. All agencies must have a prior executed service agreement with AskBio prior to any search engagement. If a candidate who was submitted outside of the AskBio agency process is hired by AskBio no fee or payment of any kind will be paid to the agency.