Senior Scientist, Immunology & Bioassays
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Job Location:
Vancouver, WA - USA
Yearly Salary:
$ 130000 - 145000
Posted on:
17 hours ago
Vacancies:
1 Vacancy
Job Summary
About Absci
Absci is a clinical-stage biotechnology company advancing novel therapeutics using generative AI. Our Integrated Drug Creation platform combines cutting-edge AI models with a synthetic biology data engine enabling the rapid design of innovative therapeutics that address challenging therapeutic targets.
Absci is a global company headquartered in Vancouver WA and maintains offices in New York City Switzerland and Serbia. Learn more at or follow us on LinkedIn (@absci) X (@Abscibio) and YouTube.
Sr. Scientist Immunology & Bioassays
Vancouver WA (onsite)
We are seeking a highly motivated collaborative and innovative scientist to join our Pharmacology and Bioassays team. The qualified candidate will have deep expertise in immunology and strong experience developing and executing in vitro and ex vivo cell-based assays to interrogate immune mechanisms and immune-mediated disease mechanisms.
This individual will be responsible for helping to establish and expand our preclinical assays will actively contribute from the bench delivering in vitro and ex vivo work packages to support and advance Abscis drug development pipeline. The successful candidate will demonstrate clear and professional communication effectively collaborate with colleagues across a highly matrixed environment and be capable of presenting scientific results to project teams.
Responsibilities
- Design develop and execute preclinical in vitro and ex vivo cell-based assays to advance therapeutic programs and support target validation MOA elucidation and lead characterization.
- Analyze and interpret complex experimental datasets to define functional activity mechanistic insight and biological relevance of therapeutic candidates.
- Identify evaluate and implement new assay models technologies and experimental approaches to strengthen disease-relevant biology and assay capabilities.
- Serve as an immunology subject matter expert integrating literature experimental data and disease biology to support project decisions and milestone advancement.
- Independently troubleshoot and optimize complex assays applying scientific judgment to resolve technical and biological challenges.
- Contribute to the development and expansion of advanced in vitro and ex vivo research capabilities within the Pharmacology & Bioassays team.
- Author and review SOPs study reports and scientific presentations to ensure clarity rigor and reproducibility.
Required Qualifications
- Ph.D. or equivalent advanced degree in Pharmacology Immunology/Inflammation Physiology cell biology or related disciplines with at least 5 years of post-PhD academic and/or industry experience in immunology immune-mediated inflammatory diseases or related field establishing direct experimental experience with the complex biology of inflammatory diseases
- Extensive experience with flow-based in-depth characterization of immune cell populations in blood and tissue samples.
- Experience with cell-based assays ELISA MSD qPCR microscopy histology/pathology (e.g. IF/IHC/ISH).
- Demonstrated expertise with complex 2D/3D functional cell-based and tissue-based assays to investigate disease biology and PK/PD relationship.
- Experience with leveraging complex data sets to characterize and establish a drugs therapeutic mechanisms of action
- Ability to be hands-on and work in the lab write protocols and execute studies leveraging Abscis in-house capabilities
- Experience working with project/research teams with functional responsibility to propose strategy analyze interpret and present complex data to inform decisions
- Ability to collaborate in writing protocols and reports
- Outstanding communication skills with demonstrated ability to make effective presentations in a broad range of settings
Preferred Skills and Experience
- Demonstrated record of leveraging in vitro/ex-vivo pharmacology models to explore antibody-based drug discovery.
- Experience with therapeutics programs leading to drug candidate nomination in one or more of the following therapeutic areas: oncology immunology/inflammation metabolic diseases
- Experience authoring study protocols reports and/or regulatory documents including IBs IND filings and/or NDAs
- Experience working with complex patient-derived cell-based 2D/3D culture systems or ex vivo tissue models
- Ability to independently generate analyze and interpret multi-omics data sets
- Strong statistical analysis skills and an ability to articulate findings and make recommendations from complex study results
- Experience mentoring scientists leading cross-functional project teams and a track record of successful management of external teams
- Experience working with vendors and CROs to execute studies analyze data and generate reports promptly
Compensation and Benefits
The salary range for this position is $130000 - 145000/year. The range provided is based on what we believe is a reasonable estimate for the base salary range for this job at the time of posting. Actual base salary pay will be based on a number of factors including skills competencies experience and other job-related factors permitted by law.
Absci offers highly competitive salaries and benefits including medical dental vision insurance unlimited vacation parental leave employee assistance program voluntary life and disability insurance annual bonus potential and 401(k) with a generous company match.
Legal authorization to work in the United States is required. Absci is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex sexual orientation gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information marital status or any characteristic protected under applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should request the recruiter or hiring manager or contact .
Required Experience:
Senior IC
Key Skills
- Laboratory Experience
- Mammalian Cell Culture
- Biochemistry
- Assays
- Protein Purification
- Research Experience
- Next Generation Sequencing
- Research & Development
- cGMP
- Cell Culture
- Molecular Biology
- Flow Cytometry
About Company
Absci streamlines biologics drug discovery to develop new therapies for patients, faster, with the data to learn, the AI to create, and the wet lab to validate.
