Intern Biology Technologies

Cytokineticsis a specialty cardiovascular biopharmaceutical company building on its over 25 years of pioneering scientific innovations in muscle biology and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction.

At Cytokinetics each team member plays an integral part in advancing our mission to improve the lives of patients. We are seeking tenacious compassionate and collaborative individuals who are driven to make a positive impact.

The Biology Technologies Intern will support research efforts focused on understanding the molecular mechanisms of hypertrophic cardiomyopathy (HCM) by characterizing disease-associated myosin mutants. This internship provides hands-on experience using biochemical and biophysical techniques to study how specific mutations affect protein structure stability and activity. The intern will contribute meaningful experimental data that informs Cytokinetics drug discovery and development programs in cardiovascular disease.

This is an onsite internship. Candidates must be able to work in person at the South San Francisco office.

Responsibilities

• Express and purify myosin protein constructs using multiple techniques (affinity ion exchange SEC)

• Assess protein purity stability and activity using SDS-PAGE Intact MS and thermal stability assays (nanoDSF).

• Evaluate compound binding and stabilization effects using methods such as Surface Plasmon Resonance (SPR) and Isothermal Titration Calorimetry (ITC).

• Maintain accurate experimental records and contribute to data analysis and interpretation.

• Participate in team meetings and provide regular project updates.

• Prepare and deliver a final presentation summarizing research findings.

Qualifications

• Havecompletedat leasttwo to four years at a US college or university at the time of the program.

• Seeking a BS degree in biochemistry and/or related fields.

• Prior coursework in biology/biochemistry/lab courses or have lab experiencerequired.

• Prior experience with protein purification preferred.

• Must be detail oriented and have a proactive attitude in support of research activities and running assays.

• Highly focused organized and motivated team player with good time management skills.

• Excellent communication skills and the ability to troubleshoot problems with team members.

• Experience in data analysis and/or presentation.

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Pay Range:

Our employees come from different backgrounds and we celebrate those differences. We are looking for the best candidates for our open roles but do not expect applicants to meet every qualification in order to be considered. If you are excited about what you could accomplish at Cytokinetics and believe you can add value to our team we would love to hear from you.

Please review ourGeneral Data Protection Regulation (GDPR) policyPRIOR to applying.

Our passion is anchored in robust scientific thinking grounded in integrity and critical thinking. We keep the patient front and center in all we do all actions and decisions are in service of the patient and their caregivers. We champion integrity ethics doing the right thing and being our best selves.

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Cytokinetics is an Equal Opportunity Employer