CK Group are recruiting for a highly motivated and experienced Principal Synthetic Biologist to join a growing biotechnological company in Newcastle on a three month fixed term contract with scope to be made permanent. A great opportunity to work in a cutting-edge field with a company at the forefront of biotechnological research and be part of a visionary team developing solutions for tomorrows challenges.
Company:A newly formed biotechnology organisation with state-of-the-art microbial engineering facilities focused on building a biological and digital platform for biological assets supply chain management.
The Role: To design execute validate and iterate complex chromosomal engineering programs in microbes. This will be a hand-on role where as Principal Biologist you will be capable of taking a biological objective from concept through engineered strains sequencing-based validation and interpretation under stress or evolutionary conditions.
Responsibilities:
- Design and execute scarred and scarless chromosomal integrationsacross diverse microbes (e.g. E. coli B. subtilis P. putida S. cerevisiae etc).
- Perform multi-round multi-locus genome engineering without marker exhaustion
- Actively use and help configure ELN and/or LIMS systems to track: strain lineages construct versions sequencing data
- Scientifically direct outsourced bioreactor work end-to-end (design oversight QC acceptance and interpretation) without being the hands-on operator of the reactors.
- Sequencing & Data Interpretation - Design DNA-seq and RNA-seq experiments aligned to engineering questions
Your Background: Essential:- PhD in synthetic biology/engineering biology with industry experience
- Must have hands-on experience in microbial strain/genetic engineering (5 - 10 years)
- Demonstrated expertise in chromosomal (not plasmid-only) modification
- Mastery of scarred and scarless genome editing techniques (CRISPR selection: Cas9/Cas12a DSB)
- Hands-on user of Electronic Lab Notebooks (ELNs) and/or Laboratory Information Management Systems (LIMS) in a synthetic biology or strain engineering environment.
Strongly Preferred- Multi-host experience across Gram-negative Gram-positive and yeast systems
- Sequencing-first engineering mindset
- Prior experience in industrial or production-adjacent strain development
- Familiarity with lab automation and digital lab systems
Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference 171 853 in all correspondence.
If this position isnt suitable but you are looking for a new role or if you are interested in seeing what opportunities are out there head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news.
CK Group are recruiting for a highly motivated and experienced Principal Synthetic Biologist to join a growing biotechnological company in Newcastle on a three month fixed term contract with scope to be made permanent. A great opportunity to work in a cutting-edge field with a company at the forefro...
CK Group are recruiting for a highly motivated and experienced Principal Synthetic Biologist to join a growing biotechnological company in Newcastle on a three month fixed term contract with scope to be made permanent. A great opportunity to work in a cutting-edge field with a company at the forefront of biotechnological research and be part of a visionary team developing solutions for tomorrows challenges.
Company:A newly formed biotechnology organisation with state-of-the-art microbial engineering facilities focused on building a biological and digital platform for biological assets supply chain management.
The Role: To design execute validate and iterate complex chromosomal engineering programs in microbes. This will be a hand-on role where as Principal Biologist you will be capable of taking a biological objective from concept through engineered strains sequencing-based validation and interpretation under stress or evolutionary conditions.
Responsibilities:
- Design and execute scarred and scarless chromosomal integrationsacross diverse microbes (e.g. E. coli B. subtilis P. putida S. cerevisiae etc).
- Perform multi-round multi-locus genome engineering without marker exhaustion
- Actively use and help configure ELN and/or LIMS systems to track: strain lineages construct versions sequencing data
- Scientifically direct outsourced bioreactor work end-to-end (design oversight QC acceptance and interpretation) without being the hands-on operator of the reactors.
- Sequencing & Data Interpretation - Design DNA-seq and RNA-seq experiments aligned to engineering questions
Your Background: Essential:- PhD in synthetic biology/engineering biology with industry experience
- Must have hands-on experience in microbial strain/genetic engineering (5 - 10 years)
- Demonstrated expertise in chromosomal (not plasmid-only) modification
- Mastery of scarred and scarless genome editing techniques (CRISPR selection: Cas9/Cas12a DSB)
- Hands-on user of Electronic Lab Notebooks (ELNs) and/or Laboratory Information Management Systems (LIMS) in a synthetic biology or strain engineering environment.
Strongly Preferred- Multi-host experience across Gram-negative Gram-positive and yeast systems
- Sequencing-first engineering mindset
- Prior experience in industrial or production-adjacent strain development
- Familiarity with lab automation and digital lab systems
Apply: It is essential that applicants hold entitlement to work in the UK. Please quote job reference 171 853 in all correspondence.
If this position isnt suitable but you are looking for a new role or if you are interested in seeing what opportunities are out there head over to our LinkedIn page (cka-group) and follow us to see our latest jobs and company news.
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