Vice President, US Compliance

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The companys R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team you will join other outstanding Revolutionariesin a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

Reporting to the Vice President US Compliance this role will support RevMeds U.S. business. This role will lead the strategy development and execution of the companys U.S. healthcare compliance program ensuring all activities are conducted ethically and in accordance with applicable laws regulations and industry codes. This executive will be instrumental in shaping and sustaining a culture of integrity as the company advances and commercializes its oncology pipeline. This attorney is responsible for program design operational implementation monitoring and enforcement - while working in close partnership with the Healthcare Law team to deliver coordinated risk-based guidance to internal business partners across the organization.

Responsibilities:

Compliance Program Leadership

• Design implement and continuously improve a comprehensive U.S. healthcare compliance program consistent with OIG Guidance PhRMA Code and applicable industry standards.

• Establish and maintain policies procedures and systems to ensure compliant operations across all U.S. commercial medical and research activities.

• Provide regular compliance updates to executive leadership including risk assessments metrics and remediation plans.

• Serve as the companys U.S. Compliance Officer and key representative in interactions with regulators external counsel and industry associations.

• Coordinate compliance guidance and initiatives with ex-US compliance teams.

Collaboration with Healthcare Law

• Partner closely with the Healthcare Law team to ensure consistency between legal interpretation and compliance operations.

• Maintain a clear functional separation of responsibilities between Compliance and Healthcare Law.

• Collaborate to deliver integrated practical guidance to internal clients particularly within Commercial Medical Affairs Clinical Development and Market Access functions.

Oncology-Specific Compliance Oversight

• Provide compliance leadership for all U.S. programs including those involving targeted therapies precision medicine and molecular diagnostics.

• Oversee compliance in complex scientific collaborations including investigator-sponsored trials (ISTs) research collaborations and co-promotion or data-sharing arrangements.

• Ensure compliant governance of interactions with oncology healthcare professionals (HCPs) key opinion leaders (KOLs) and academic research centers.

• Oversee U.S. aggregate spend transparency and Sunshine Act reporting obligations including oncology-specific speaker programs congress sponsorships and advisory boards.

• Provide compliance support for patient access programs patient support services and specialty distribution channels ensuring compliant interactions with patients caregivers and advocacy groups.

Monitoring Training and Investigations

• Develop and implement risk-based compliance training for field and headquarters staff tailored to oncology business activities (e.g. clinical data dissemination compassionate use programs).

• Design and oversee monitoring and auditing plans covering commercial field conduct grants consulting arrangements and medical education.

• Lead investigations into potential violations ensuring timely thorough resolution and corrective actions.

• Track analyze and report compliance metrics and trends to management and governance bodies.

Cross-Functional Collaboration and Leadership

• Serve as a trusted advisor to senior leadership and cross-functional teams on compliance risks and mitigation strategies.

• Collaborate with Legal Medical Affairs Clinical Operations and Market Access on compliant program design and execution.

• Partner with Finance HR and Internal Audit to ensure unified corporate risk management.

• Build lead mentor and develop a team of compliance professionals committed to excellence and integrity.

Required Skills Experience and Education:

• J.D. from an accredited U.S. law school and member in good standing of a U.S. State Bar.

• 12-15 years in healthcare compliance or legal roles within the biotechnology pharmaceutical or oncology industry.

• In-depth understanding of U.S. healthcare laws including Anti-Kickback Statute False Claims Act FDA promotional regulations FCPA and data privacy laws.

• Proven ability to build lead and scale compliance programs for commercial or late-stage clinical oncology companies.

• Experience supporting oncology-specific programs such as scientific exchange KOL engagement and patient access models.

• Strong leadership communication and influencing skills with the ability to work collaboratively across legal scientific and business functions.

• Strategic and pragmatic compliance mindset with strong business acumen.

• High ethical standards and sound judgment.

• Ability to lead through influence in a dynamic matrixed biotech environment.

• Strong understanding of oncology market dynamics scientific communication and patient-centric engagement.

• Commitment to fostering a culture of integrity transparency and continuous improvement.

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