PhD in Personalized hemodynamic modelling of carotid artery stenosis for stroke prediction

Introduction

• Are you fascinated by cardiovascular biomechanics and its application to medical decision support
• Are you eager to be trained to develop multi-level thrombosis risk prediction models by integrating cell- thrombus- and organ-level insights
• Are you passionate about being part of a prestigious MSCA doctoral network working on revolutionizing personalized medicine through cutting-edge in silico in vitro and in vivo technologies to understand predict and treat thrombosis

Job Description

At the faculty of Biomedical Engineering at Eindhoven University of Technology a PhD-position is available within the Thromborisk project a Marie Sklodowska-Curie Actions (MSCA) Doctoral Network funded by the EU. The position is open for appointment during the course of 2026-2030 with a duration of 48 months hosted by TU/e and includes secondments at the partner institutes within the consortium for a cumulative period of 12 months.

As a doctoral candidate (DC) you will be embedded in the Cardiovascular Biomechanics group led by Prof. Huberts which focuses on computational and experimental biomechanical analysis of the cardiovascular system and its application to clinical diagnosis prognosis and intervention. Within this collaborative environment you will work closely with Maastricht University Medical Center participate in secondments and supervise BSc/MSc students on related projects.

Your main challenge will be to develop personalized in silico and in vitro hemodynamic models of the carotid artery bifurcation. These models will form the basis of a tool to evaluate the potential for carotid artery thrombus embolization ultimately contributing to clinical trials aimed at predicting patient-specific stroke risk.

This position offers the opportunity to contribute to research with high societal impact: improving stroke risk prediction and supporting personalized treatment strategies.

Research Programme Description

ThromboRisk European Doctoral Network From cells to systems: Pioneering multi-level thrombosis risk prediction models consortium is funded by the European Union under Grant Agreement No. . It groups 10 hiring universities: Eindhoven University of Technology (NL) University of Maastricht (NL) University of Amsterdam (NL) Catholic University Leuven (BE) Charité Universitätsmedizin Berlin (DE) University College London (UK) Transsilvania University of Brasov (RO) SANO Centre for Computational Personalized Medicine (PL) University of Leeds (UK) and University of Bern (CH).

ThromboRisk will develop an integrated platform to advance our understanding of thrombosis across biological scales combining mechanobiology biochemistry pathophysiology and computational modelling. For this inclusion to occur each DC will develop through their research a unique contribution to the multi-level thrombosis risk prediction framework addressing specific aspects of thrombus formation growth rupture and clinical impact. This hands-on training is supplemented with several scientific professional courses and an immersive training program where the DCs can fine-tune their skills for the jobs of tomorrow while addressing the societal challenges of the ThromboRisk program.

Job Requirements

We are looking for a candidate who meets the following requirements:

• You are creative and ambitious hard-working and persistent.
• You have a MSc degree in Biomedical Engineering Mechanical Engineering Physics or any other relevant program.
• You have theoretical and applied knowledge or interest in biomechanical and numerical modelling and preferably also AI.
• You have a research-oriented attitude
• You have good communicative skills and the attitude to partake successfully in the work of a research team.
• You have the ability to work in an interdisciplinary team and interested in collaborating with industrial partners.
• You are motivated to develop your teaching skills and coach students.
• You have a good command of the English language (Spoken and Written Proficiency C1).

Conditions of Employment

A meaningful job in a dynamic and ambitious university in an interdisciplinary setting and within an international network. You will work on a beautiful green campus within walking distance of the central train addition we offer you:

• Full-time employment for four years with an intermediate evaluation (go/no-go) after nine months. You will spend a minimum of 10% of your four-year employment on teaching tasks with a maximum of 15% per year of your employment.
• Salary and benefits (such as a pension scheme paid pregnancy and maternity leave partially paid parental leave) in accordance with the Collective Labour Agreement for Dutch Universities scale P (min. 3059 max. 3881 gross salary). This salary is in accordance with the MSCA Call 2024 regulations for Doctoral Researchers and will be paid from the relevant monthly gross allowances (gross living allowance 4.010 per month; mobility allowance 710 per month; family allowance 660 per month only if applicable).
• A year-end bonus of 8.3% and annual vacation pay of 8%.
• High-quality training programs and other support to grow into a self-aware autonomous scientific researcher. At TU/e we challenge you to take charge of your own learning process.
• An excellent technical infrastructure on-campus childrens day care and sports facilities.
• An allowance for commuting working from home and internet costs.
• A Staff Immigration Team and a tax compensation scheme (the 30% facility) for international candidates.

About us

Eindhoven University of Technology is a leading international university within the Brainport region where scientific curiosity meets a hands-on mindset. We work in an open and collaborative way with high-tech industries to tackle complex societal challenges. Our responsible and respectful approach ensures impact today and in the future. TU/e is home to over 13000 students and more than 7000 staff forming a diverse and vibrant academic community.

The TU/e offers academic education that is driven by fundamental and applied research. We combine scientific curiosity with a hands-on educational philosophy is based on personal attention and room for individual ambitions and talents. Our research meets the highest international standards of quality. We push the limits of science which puts us at the forefront of rapidly emerging areas of research.

The university is located near the central train station of Eindhoven and the Eindhoven city center. It is well connected to Eindhoven airport and Schiphol airport can be easily reached by train.

The Department of Biomedical Engineering offers top-level education and research in one of the most relevant and exciting scientific disciplines of the 21st century: engineering combining engineering and life sciences through challenge-based learning and a multidisciplinary approach in collaboration with hospitals industry and others the department addresses the great challenges of the future striving to improve healthcare and society as a whole.

Information

Do you recognize yourself in this profile and would you like to know more Please contact the hiring manager Prof. Wouter Huberts .

Visit our website for more information about the application process or the conditions of employment. You can also contact Sascha Sanchez van Oort HR Advisor .

Curious to hear more about what its like as a PhD candidate at TU/e Please view the video.

Are you inspired and would like to know more about working at TU/e Please visit our career page.

Application

We invite you to submit a complete application by using the apply button. The application should include a:

• a cover letter in which you describe your motivation and qualifications for the position including the topic of your MSc thesis project.
• a curriculum vitae (including contact details of at least three references). Kindly note that we may reach out to references at any stage of the recruitment process. We recommend notifying your references upon submitting your application.
• a list of BSc and MSc courses and grades.

Ensure that you submit all the requested application documents. We give priority to complete applications.

We look forward to receiving your application and will screen it as soon as possible. The vacancy will remain open until the position is filled.

Please note

• You can apply online. We will not process applications sent by email and/or post.
• A pre-employment screening (e.g. knowledge security check) can be part of the selection procedure. For more information on the knowledge security check please consult the National Knowledge Security Guidelines.
• Please do not contact us for unsolicited services.