Executive Director, Head of Information Technology, Japan

Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The companys R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team you will join other outstanding Revolutionaries in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

The Opportunity:

We are seeking an experienced IT Leader to establish and oversee the set up and execution of all aspects of IT operations in Japan. This role will serve as the primary technology partner for business functions in Japan also acting as the bridge between local stakeholders and global Information Sciences (IS) and Information Technology (IT) teams ensuring that IS/IT needs are met in alignment with global platforms delivering end-to-end solutions for local implementation while driving operational excellence in IS/IT services. This leader may also help build and scale the IT function to other countries in the Asia Pacific region through a balanced model of internal team development and strategic vendor partnerships to deliver agile high-quality support across the region.

Reporting directly to the President & Representative Director Japan this individual will collaborate closely with country and regional leaders as well as global Information Sciences and Information Technology (IS/IT) partners. The role also dotted-line reports to the VP Commercial & Medical Affairs Information Systems. The position requires versatilitybalancing the establishment of local capabilities with the development of scalable solutions that integrate seamlessly into global frameworks.

Commercial and Medical Affairs Systems

• Serve as the primary liaison between Japan and global Information Systems teams fostering cross-functional collaboration while maintaining data governance and separation of processes.

• Partner with business leaders to develop prioritized roadmaps and capture requirements ensuring alignment with global IS/IT platform roadmaps while tailoring solutions to country/regional needs.

• Act as an effective liaison by proactively communicating priority needs for the APAC/Japan region and working closely with other regions to align on shared priorities expectations and consistent working norms.

• Support rollout localization and adoption of global platforms (e.g. CRM digital engagement Omnichannel marketing medical information medical content management field engagement tools).

• Partner with local Commercial Supply Chain and Quality teams to ensure IS/IT systems supporting product distribution logistics and product release operate reliably and comply with local regulatory standards.

• Oversee localization and validation of IS/IT systems to meet Japan-specific business and regulatory needs including language documentation and integration with local platforms.

• Provide Tier 12 application support in partnership with global support teams ensuring seamless end-to-end service delivery.

• Lead change management for new IS/IT systems including user testing training communications and stakeholder alignment to ensure successful adoption and continuous improvement.

Information Technology and Security

• Establish and manage relationships with local managed service providers and vendors.

• Collaborate with global IT infrastructure teams to ensure reliable and secure delivery of core IT services (network hardware collaboration platforms endpoint management).

• Oversee system enhancements integrations and facilitate compliance with Japanese data production and pharmaceutical regulations including pharmacovigilance promotional review and data privacy (APPI PMD Act).

• Manage onboarding and offboarding processes ensuring timely provisioning/deprovisioning of accounts and devices aligned with local and global IT policies and security standards.

• Ensure adherence to global IT service management and change control processes including incident request and problem management while coordinating escalations with global support teams.

• Partner with global Information Security teams to ensure adherence to enterprise security standards policies and regulatory requirements.

• Lead Japan-specific implementation and oversight of security controlsincluding identity and access management data protection compliance monitoring cybersecurity training audits and incident response coordination with global security operations.

R&D Systems:

• Partner with global R&D IS to enable secure access to research and clinical platforms in compliance with regulatory requirements (GxP CTMS EDC RIM eCTD PV safety database etc).

Required Skills Experience and Education:

• Bachelors degree (or equivalent).

• Minimum of 12 years of experience delivering technology services and support including Commercial systems.

• At least 5 years of experience leading Japan IT activities within a life sciences organization.

• Proven leadership experience building and scaling IT teams in emerging country operations including recruitment performance management and fostering a culture of accountability and continuous improvement.

• Hands-on knowledge of IT infrastructure end-user services and cybersecurity practices.

• Strong understanding of Commercial data ecosystems (CRM digital engagement social and third-party sources) and their integration across platforms.

• Knowledge of master data management (MDM) data warehousing principles and technologies and enterprise analytics environments (e.g. Databricks Snowflake) supporting Commercial and Medical insights.

• In-depth knowledge of GxP systems regulatory compliance and data privacy frameworks and processes.

• Experienced in leading organizational change for IT initiatives driving user adoption through clear communication stakeholder alignment and compelling storytelling.

• Collaborative and effective in building rapport across global regional local and functional teams.

• Comfortable with ambiguity and skilled at defining operating models processes and roles while simultaneously implementing capabilities.

Preferred Skills:

• Experience supporting pre-commercial or commercial launches in pharma strongly preferred.

• Familiarity with Omnichannel principles and technology platforms in life sciences.

• Experience with an Oncology launch is desired.

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