Principal Computational Biologist (Portfolio Generation)
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Monthly Salary:
Posted on:
13 hours ago
Vacancies:
1 Vacancy
Job Summary
PrincipalComputationalBiologist(Portfolio Generation)(Under the leadership ofAlex Kalinka)
Internally this is known as PrincipalBioinformatician (Portfolio Generation)
57000- 70900plusbenefits
Reports to:Group Leader Quantitative Biology
Directorate:Research & Innovation
Contract:Permanent
Hours:Full time 35 hours per week
Location:CambridgeBabraham Research Campus(Limited flexibility 3-4 days per week on site)
Closing date:25 January 202623:55
This vacancy may close earlier if ahigh volumeof applications is received or once a suitable candidate is found therefore we strongly recommend that you apply early to avoid disappointment.Please let us know if thereisanythingabout the recruitment process that you would like to discussin particular ifthere are any changes or adjustments that would make it easier for you to apply. Please contactoras soon as possible.
Visa sponsorship:Cancer Research UKcanconsider visa sponsorship for this vacancy. If this applies to you please ensure that this is clearly marked on your application.
Recruitment process:1ststage interview viaMicrosoftTeams 2ndstage will include a presentation followed bycompetency-basedquestions on-site
Interview date:We will be booking in 1st stage interviews on an ongoing basis 2nd stage in planned for 3 and 6 of February
At Cancer Research UK we exist to beat cancer.
Cancer Research Horizons are looking to recruit apassionate scientificprofessional toset and drive our computational strategy forthe discovery and validation of novel oncology targets including through the analysis of patient data.
About Cancer Research Horizons
As the worlds biggest medical research charitywevehelped bring eleven new cancer drugs to market. However there is still an urgent need to bring more effective treatments to patients faster.
We have recently developeda new approachto driving therapeutic innovation through the creation of Cancer Research Horizons (CRH). We have brought together Cancer Research UKs established drug discovery teams under one organisation and leadership team combining our unique pipeline of cancer biology expertise and access to CRUKs world-class academic network cutting edge technology platforms and clinical expertise to 1) bring new treatments to patients faster and 2) tackle the biggest challenges in discovering cancer drugs by seeking out more radical ideas and embracing risk in our bid to achieve success.
Based at sites in Cambridge the CRUK Scotland Institute inGlasgowandNewcastle University Cancer Research Horizons employs 200 staff from both industrial and academic backgrounds
This is a new role for the team and realchance to make a tangible impact from day one.We are looking for candidates who can bring strong experience of AI and machine learning tounlock the power of real patient data.Werejust scratching the surface andnowsyour chance to lead the way.InIn thisroleyou will become an integral part of the Cancer Research Horizon Drug Discovery team helping to progress novel cancer targets towards patient benefit.Furthermoreweactively encourage our colleagues to celebrate our science by attending conferences presenting posters giving talks at events and publishing papers.
What will I be doing
Our new strategy sets out to bring deeper mechanistic understanding at the molecular and cellular level to all stages of projects from idea to pre-clinical Candidate. Reporting directly to the Leader of our Quantitative Biology teamwe are looking for an experienced computational biologist todevelop evaluate and apply both existing and novel machine learning and AI approaches to integrate multi-modal oncology datasets to generate novel testable hypotheses.As aPrincipalComputationalBiologistyou will work closely with bench scientists bioinformaticians and statisticians to design functional genomics experiments to test computational predictions and support the analysis and interpretation of downstream validation experiment
In this role you will:
Set and driveourcomputational strategy for the analysis ofpatient multi-omics datasetsto discover novel oncology targets.
Evaluate develop and implement newand existingmachine learning and AI approaches to uncover actionable biological insights from large multi-modal oncology datasets.
Provide deepexpertiseincomputational biologyand its role inoncologydrug discovery.
Foster a culture of continuous improvement for ourcomputational and analytical approaches.
Providescientificand strategicleadershipincomputational biologyacrossCRH.
Communicate effectively to influence multiple stakeholdersand collaborateacross projects and sites including externally.
Promote scientific excellence through external publicationandpresentations.
Play a pivotal role in training and developing colleagues.
Whatarewelooking for
PhD in bioinformatics data science or equivalent
Experience within a drug discovery environmentspecifically a pharma or biotech company
Experienced in the use and development of machine learning and AI approaches for the integration and analysis of large multi-omics datasets
A strategic thinker with proven scientific leadership including through matrix management
Programming experience with tools such as Python
Experience adhering to good coding hygiene practices such as documentation testing and code review
Excellent communication skills ability to describe complex science in an engaging and inclusive manner.
Ability tobuild open and honest relationships andinfluence multiplestakeholders.
Ability to workcollaborativelyacrossprojects and sites also externally
Our organisation values are designed to guide all that we do.
Bold:Act with ambition courage and determination
Credible:Act with rigour and professionalism
Human: Act to have a positive impact on people
Together:Act inclusively and collaboratively
Were looking for people who can believe in and embody these organisation values and can use them to drive forward progress against our mission to beat cancer.
If youre interested in applying and excited about working with us but are unsure if you have the right skills and experience wed still love to hear from you.
What will I gain
Wecreate a working environment that supports your wellbeing andprovide agenerous benefits package a wide range of career and personal development opportunities and high-quality tools. Ourpolicies and processes enable you toimprove your work-life balance take positive steps in your career and achieve your personal wellbeing goals.
You can explore our benefitsby visiting ourcareers web page.
How do I apply
We operate an anonymised shortlisting process in our commitment to equality diversity and inclusion. CVs are required for all applications; but we wont be able to view them until we invite you for an interview. Instead we ask you to complete the work history section of the online application form for us to be able to assess you fairly and objectively.
For more information on this career opportunity pleasevisit our websiteor contact us at.
Our vision is to create a charity where everyone feels like they belong benefits from and participates in the work we do. We actively encourage applications from people of all backgrounds and cultures in particular those from ethnic minority backgrounds who are currently under-represented.
We want to see every candidate performing at their best throughout the job application process interview process and whilst at work. We therefore ask you to inform us of any concerns you have or any adjustments you might need to enable this to happen. Please contact or 0as soon as possible.
Unfortunately we are unable to recruit anyone below the age of 18 so that we can protect young people from health & safety and safeguarding risks.
Required Experience:
Staff IC
Key Skills
- Laboratory Experience
- Transfection
- Bioinformatics
- DNA Isolation
- Genetics
- PCR
- R
- Biochemistry
- Next Generation Sequencing
- Cell Culture
- Molecular Biology
- Research Laboratory Experience
