Postdoctoral Researcher in Cancer Genomics

Leuven - Belgium

Monthly Salary: Not Disclosed

Posted on: 17 hours ago

Vacancies: 1 Vacancy

Job Summary

Chart tumour evolution using cutting-edge long-read and single-cell multiomics

Who we are

The Integrative Cancer Genomics lab (Jonas Demeulemeester) is embedded within the VIB KU Leuven Center for Cancer Biology and two of the research departments of the VIB Life Sciences Institute within KU Leuven one of the worlds top 50 universities. Our diverse and international center is located on the University Hospital Campus Gasthuisberg where it hosts about 230 researchers and staff creating a vibrant ecosystem where fundamental research meets clinical practice.

What we do

Our cells continuously accumulate genetic and epigenetic changes that fuel somatic evolution through drift and selection. Over time these processes turn tissues into molecular mosaics containing competing subclones often carrying cancer driver mutations. We aim to bridge the gap between somatic genotypes and phenotypes using cutting-edge approaches including long-read sequencing (PacBio Nanopore) single-cell multiomics (e.g. doi: 10.1101/2025.09.08.674950) and AI/machine learning. We work closely with clinicians to translate our findings into clinical practice focusing on genomically complex sarcomas and haematological malignancies.

What you will do

As a postdoctoral researcher you will:

Analyse multiomic long-read and single-cell data from patient samples to develop novel biological insights
Contribute to recently funded projects on genomically complex sarcomas and somatic mosaicism with opportunities to develop your own research
Develop and apply computational tools and workflows for integrating multimodal datasets
Collaborate effectively across disciplines—working with clinicians biologists and data scientists
Present your work at international conferences and publish in high-visibility journals

Who we are looking for

We are seeking a motivated computational biologist with a passion for cancer genomics and a drive to tackle complex biological questions.

Essential:

PhD (or studying towards a PhD) in computational biology bioinformatics genomics statistics physics or a related quantitative field
Demonstrated ability to analyse large-scale sequencing data using R Python or equivalent
A self-motivated team player who thrives in a collaborative international environment
Excellent communication skills in English (written and spoken)

Nice to have:

Experience with cancer genomics single-cell analysis or long-read sequencing data
Familiarity with high-performance computing environments
Track record of publications in peer-reviewed journals

What we offer

Cutting-edge infrastructure: state-of-the-art sequencing technologies single-cell platforms and high-performance computing
(Inter)national network: collaborate locally with international consortia and leading cancer centres (UCL Francis Crick Institute MD Anderson Cancer Center)
Career development: active support through mentorship opportunities to lead projects supervise PhDs and apply for independent fellowships
Vibrant community: active PhD and postdoc associations seminar series and a stimulating inclusive research environment
Competitive package: salary and benefits for 4 years according to VIB/KU Leuven scales with opportunities for training and conference attendance
Starting date: as soon as possible (flexible)

How to apply

Please submit your application including a detailed CV motivation letter and contact details of 23 references directly via the online application tool. Review of applications will begin immediately and continue until the position is filled.

More information

Lab website: Center for Cancer Biology:

VIB Center for AI and Computational Biology: questions:

KU Leuven and VIB aim to be inclusive respectful and socially safe communities. We embrace diversity between individuals and groups as an added value. We do not accept any form of discrimination. If you have any questions about accessibility or support please contact us.

Chart tumour evolution using cutting-edge long-read and single-cell multiomicsWho we are The Integrative Cancer Genomics lab (Jonas Demeulemeester) is embedded within the VIB KU Leuven Center for Cancer Biology and two of the research departments of the VIB Life Sciences Institute within KU Leuven...