Associate Principal Scientist, Vector Design
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Job Location:
Santa Monica, CA - USA
Monthly Salary:
$ 134892 - 202339
Posted on:
4 days ago
Vacancies:
1 Vacancy
Job Summary
AstraZeneca is looking for a highly motivatedexperiencedand strategicAssociate Principal Scientist Vector Designtojoinour Viral VectorNew ModalitygroupwithinAstraZenecasProcessScience and Technology (PSAT)Cell Therapy Development and Operation (CTDO) organization. The successful candidate will bringa combination oftechnicalexpertiseinprocess developmentandproject management skills.He/sheisresponsible forleadingviral vectorprocess development projectstoensuretheymeet quality regulatory and business goals on time.He/shewillcoordinate cross-functional teamsmanagesproject timelines and resources andcommunicatesprogress to stakeholders.This rolewilloperatestrategically in a highly collaborative environment.Thisrole can be based in either Santa Monica CA or Gaithersburg MD.
Responsibilities:
Viral vector process design:Leadingsupportingthedesign and developmentofscalable cost-effective GMP compliance LVV manufacturing processes to support a variety of ex vivo and in vivo cell therapy programs
Project planning and execution:Initiating planning and overseeing the entireviral vector process developmentproject lifecycle frominitialconcept lab buildto manufacturingtechtransfer
Cross-functional team leadership:Managing and aligning diverse teams including scientists and engineers to ensure project goals are met
Technical oversight:Partnering with technical leads to define deliverables troubleshoot issues and ensure the scientific and technical aspects of process development are sound
Timeline and budget management:Developing and managing project timelines adjusting as needed and ensuring the project stays within budget
Regulatory compliance:Ensuring all project activities adhere to relevant regulations such as GMP and ICH guidelines
Stakeholder communication:Serving as the main point of contact providing updates to clients and internal stakeholders and managing project communications
Supplyandlab management: managingvendors/suppliers/service providers to ensuresmoothviral vectorlaboperationsas needed
Education and Experience:
PhD in relevant Engineering or Science majors and5 years of related industry experience or MS with8 years of related industry experience cell and gene therapy experience preferred
Title will becommensuratewith qualification and experience
Preferred Qualifications:
Previousexperience inviral vectororCAR-Tprocess developmentandproject management
Experience managing scale-up tech-transfer and implementation ofmanufacturingprocesses at internal and external manufacturing partners
Knowledge of cGMP and Quality systems requirements FDA guidance relevant to gene and cell therapy
Proven ability to manage matrixed projects and tasks to completionanticipatingand elevating risks and obstacles and adjusting to effective contingency plans
Strong organization and record-keeping skills including ability to manage multiple responsibilities in parallel
A highly collaborative working styletrack recordof successful performance in a matrixed team environment
Strongsoft skillsincludingcommunication leadership adaptability and problem-solving skills
The annual base pay for this position ranges from $134892.80 - $202339.20. Base pay offered may vary depending on multiple individualized factors including market location job-related knowledge skills and addition our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program 401(k) plan; paid vacation and holidays; paid leaves; and health benefits including medical prescription drug dental and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an at-will position and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.
Date Posted
10-Nov-2025Closing Date
27-Nov-2025Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.
Required Experience:
Staff IC
Key Skills
- Machine Learning
- Python
- Data Science
- AI
- R
- Research Experience
- Sensors
- Drug Discovery
- Research & Development
- Natural Language Processing
- Data Analysis Skills
- Toxicology Experience
About Company
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, ... View more
