Scientist, Cell Engineering

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profile Job Location:

Dallas, IA - USA

profile Monthly Salary: Not Disclosed
Posted on: 09-11-2025
Vacancies: 1 Vacancy

Job Summary

The Scientist will derive non-model organism primary cell lines conduct assays corresponding to cell health characterize lines and occasionally perform microsurgeries. The candidate will be part of a core team responsible for optimizing and characterizing for lines derived in house and support other parts of the cell core team in gene editing workflows. This position reports to the Manger of Primary Cell and Production sub-team with the Cell Engineering and Production (CEP) core team.

This position is based on-site in Dallas TX. Relocation assistance is available.

Duties and Responsibilities:

  • Isolate expand and maintain high-quality primary cell cultures from diverse non-model animal tissues.
  • Innovate then execute experiments to generate and characterize primary cells from non-model mammalian organisms develop functional assays assess and interpret experimental workflows
  • Work with team members to coordinate and execute surgical procedures.
  • Work with team members to assess efficiency of workflows through cellular assays and NGS sequencing approaches
  • Work on project milestones
  • Attend lab meetings prepare reports and presentations on the progress of projects
  • Great organizational skills and excellent laboratory record maintenance

Required Schedule:

  • Once onboarding is complete this role will have a non-traditional workweek. The individual in this role will have 2 days off per week but that may not be Saturday/Sunday. The individual must be available to work weekends.

Required Skills and Abilities:

  • Expert knowledge of primary cell derivation culture propagation and biobanking
  • Expert knowledge and hands-on experience in CRISPR gene editing including proficiency with multiple gene delivery methods such as chemical transfection electroporation and LNP delivery.
  • Experience with flow cytometry immunostaining confocal microscopy
  • Microdissection experience
  • Surgical experience
  • Strong Aseptic Technique and ability to work with antibiotic free culture
  • Strong written and oral communication skills as well as creative problem-solving skills
  • Enjoys the fast-paced startup environment and teamwork
  • Exceptional organizational skills multitasking and attention to detail.
  • Strong emotional intelligence and passion for building relationships across all levels.
  • Ability to function well in a growth-oriented nimble environment.

Preferred Experience:

  • Experience with automated cell culture workflows.
  • Previous work with mESC editing pipelines

Education and Experience:

  • PhD in biological sciences stem cell biology genetics or related field. BS/MS with significant relevant experience will also be considered
  • 4 years hands-on expertise in mammalian cell culture systems

What Colossal Offers You:

  • Medical dental and vision coverage
  • Unlimited PTO and company holidays so you can rest and recharge
  • Flexible spending accounts (FSA)
  • Company matched 401k retirement plan
  • Paid parental leave up to 12 weeks
  • Education reimbursement
  • An opportunity to help us return the Earth to a healthier state

The team at Colossal is committed colorful passionate intelligent collaborative creative experienced scientific and world-class. That sounds like a lot to fit into one building. Thats why we are spread out in several locations that include laboratories test facilities academic institutions libraries and offices.

Through it all however we maintain a culture of positivity hope happiness and belief that were doing something big. Something Colossal.

Colossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive.

EEO is the Law

Search Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house.

Colossal is proud to be named a Best Place to Work by BuiltIn for 3 years in a row across multiple categories inand 2025:

  • #1 on the 50 Best Startups to Work For in Dallas in 2023!
  • 100 Best Midsize Places to Work in Dallas in 2024 & 2025
  • 100 Best Places to Work in Dallas TX (All Size Employers) in 2024 & 2025

Built In 2025 Award Lists

Great Place to Work Certification Page

Most Loved Workplace Certification Page - Proud to be certified as a most loved workplace including: most loved CEO most loved workplaces for LGBTQ most loved workplaces for women and most loved workplaces for young professionals.

Newsweeks Most Loved Workplaces 2024 Award List - Excited to be amongst the winners of Newsweeks 2024 Most Loved Workplaces!

The Scientist will derive non-model organism primary cell lines conduct assays corresponding to cell health characterize lines and occasionally perform microsurgeries. The candidate will be part of a core team responsible for optimizing and characterizing for lines derived in house and support other...
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Key Skills

  • Laboratory Experience
  • Immunoassays
  • Machine Learning
  • Biochemistry
  • Assays
  • Research Experience
  • Spectroscopy
  • Research & Development
  • cGMP
  • Cell Culture
  • Molecular Biology
  • Data Analysis Skills