Scientist II, Synthetics Laboratory

Who is USP

The U.S. Pharmacopeial Convention (USP) is an independent scientific organization that collaborates with the worlds top authorities in health and science to develop quality standards for medicines dietary supplements and food ingredients. USPs fundamental belief that Equity Excellence manifests in our core value of Passion for Quality through our more than 1300 hard-working professionals across twenty global locations to deliver the mission to strengthen the supply of safe quality medicines and supplements worldwide.

At USP we value inclusivity for all. We recognize the importance of building an organizational culture with meaningful opportunities for mentorship and professional growth. From the standards we create the partnerships we build and the conversations we foster we affirm the value of Diversity Equity Inclusion and Belonging in building a world where everyone can be confident of quality in health and healthcare.

USP is proud to be an equal employment opportunity employer (EEOE) and affirmative action employer. We are committed to creating an inclusive environment in all aspects of our workan environment where every employee feels fully empowered and valued irrespective of but not limited to race ethnicity physical and mental abilities education religion gender identity and expression life experience sexual orientation country of origin regional differences work experience and family status. We are committed to working with and providing reasonable accommodation to individuals with disabilities.

Brief Job Overview

The role is engaged in the synthesis and delivery of USP Reference Standard candidate materials and API impurities through design and development of cost-effective synthetic routes. Candidate should carry literature search using scientific databases and work on planning and execution of synthesis of target molecules in mg to multigram/KG scale. Candidate should ensure the completion of assigned tasks as per timelines prepare project reports communicate with the team and update on the project progress. Candidate should be adherent to quality management systems (QMS) and lab safety practices.

How will YOU create impact here at USP

In this role at USP you contribute to USPs public health mission of increasing equitable access to high-quality safe medicine and improving global health through public standards and related addition as part of our commitment to our employees Global People and Culture in partnership with the Equity Office regularly invests in the professional development of all people managers. This includes training in inclusive management styles and other competencies necessary to ensure engaged and productive work environments.

The Scientist II has the following responsibilities:

• Carry out literature search related to assigned projects using various scientific data base.
• Design synthetic routes for the target molecules and prepare project proposals with tentative cost estimates
• Procure key raw materials and reagents required for the project
• Perform the reactions in small as well as large scale in the lab for the synthesis of target compounds
• Purification of compounds through various techniques such as crystallization column chromatography and advanced flash purification systems.
• Troubleshooting synthesis and purification issues
• Contributing effectively towards more challenging and complex projects through innovative methodologies
• Ensuring the availability of chemicals and equipment required for the projects and forward the purchase requisitions

• Interpretation of analytical data of synthesized compounds by IR NMR Mass Spectra Elemental analysis etc.
• Produce quality materials as per customer requirement
• Packaging of synthesized compounds
• Plan execute and complete the projects as per the timelines
• Document all experiments conducted as per QMS guidelines.
• Responsible to ensure the calibrations of the equipment as per the schedule
• Periodic check of the assigned equipment to ensure its working condition
• Work on any other assigned tasks/ lab management activities.

• Conversant with lab safety norms and strictly follow them.
• Communicate within the team and cross functional teams
• Learn and practice Diversity Equity Inclusion & Belonging culture.

Who is USP Looking For

The successful candidate will have a demonstrated understanding of our mission commitment to excellence through inclusive and equitable behaviors and practices ability to quickly build credibility with stakeholders along with the following competencies and experience:

• M Sc (Organic Chemistry) from a reputed university with minimum 3-6 years of industrial experience in CDMO/CRO/ API Process R&D
• Strong background in synthetic organic chemistry Interpretation of spectral data of compounds based on IR NMR HPLC Mass Elemental analysis and other analysis.
• Ability to independently search literature design optimize and develop synthetic processes for any given target molecules/APIs.

• Hands on experience in process development of diverse chemical class of APIs/ NCEs on lab scale.
• Excellent troubleshooting skills in synthesis and purification of target compounds.
• Should possess good verbal and written communication skills.
• Should possess good organizational communication and interpersonal skills.

Additional Desired Preferences

• Extensive knowledge of a wide range of organic reactions and hands-on experience in handling various sensitive chemicals/reagents.
• Should have exposure to GMP/GLP environment and documentation procedures. Have good practical documentation & presentation skills.
• Attention to detail strategic thinking and problem-solving skills.
• Demonstrated ability to work both independently and as a member of a team with a passion for quality

Supervisory Responsibilities

No

Benefits

USP provides the benefits to protect yourself and your family today and tomorrow. From company-paid time off and comprehensive healthcare options to retirement savings you can have peace of mind that your personal and financial well-being is protected.

Note: USP does not accept unsolicited resumes from 3rd party recruitment agencies and is not responsible for fees from recruiters or other agencies except under specificwritten agreement with USP.