Research Associate Oligonucleotide Chemistry

Tübingen - Germany

Yearly Salary: EUR 46000 - 52000

Posted on: 30+ days ago

Vacancies: 1 Vacancy

Job Summary

AIRNA is a biotechnology company with a mission to be the leading RNA editing company delivering precision therapies to patients with rare and common diseases.

AIRNA is harnessing advances in genetics to develop transformative RNA-editing medicines that improve human health. Our proprietary platform is based on groundbreaking research by pioneers of the field and company co-founders Thorsten Stafforst (University of Tübingen) and Jin Billy Li (Stanford University) and enables optimal potency safety and delivery. AIRNA is advancing a robust pipeline of therapeutic candidates that are designed to provide functional cures for severe or chronic diseases by repairing harmful genetic variants or introducing beneficial variants promote optimal health.

AIRNA has raised $245 million in financing from a world-class syndicate of investors including Arch Venture Partners Forbion Venrock Healthcare Capital Partners RTW Investments Nextech Invest and ND Capital. We value teamwork resilience excellence human and health and have a diverse team at both our headquarters in Cambridge MA and our research operations in Tübingen Bio Germany GmbH is seeking a highly motivated and collaborative

Tasks

Support the synthesis of oligonucleotides on mouse and non-human primate (NHP) scale (Mermade Cytiva K&A) for research and pre-clinical use
Apply and develop processing workflows and procedures to enhance time efficiency and product quality
Run systematic reaction optimizations on automated DNA synthesizers
Perform conjugation reactions of small molecules with oligonucleotides
Document and report experimental results
Write standard operating procedures (SOPs)
Maintain a clean and safe working environment
Pro-actively communicate with other team members and colleagues within the company

Requirements

MSc in organic chemistry or related (or BSc with min. 2 years of industry experience)
Familiarity with oligonucleotide chemistry and previous work experience is considered a plus
Solid wet lab skills: pipetting manipulating liquids handling chemicals work in laminar flow hood etc.; familiarity with HPLC equipment is considered a plus familiarity with oligonucleotide synthesizers is a big plus
Hands-on approach and can-do attitude precision and attention to detail
Team player with excellent communication skills in spoken and written English German is a plus
A valid work permit for Germany is mandatory

Benefits

An exciting role in a promising high-impact research field.
The opportunity to contribute to the development of future medicines.
Work within a fast-growing startup that values innovation and scientific excellence.
Collaborate with a diverse enthusiastic and international team.
Be part of the ONE AIRNA culture.
Attractive compensation stock options and additional benefits.
The position involves working across both Germany and the US and intercultural exchange opportunities.

The position is based in Tübingen Germany.

AIRNA is a biotechnology company with a mission to be the leading RNA editing company delivering precision therapies to patients with rare and common diseases.AIRNA is harnessing advances in genetics to develop transformative RNA-editing medicines that improve human health. Our proprietary platform ...

AIRNA is a biotechnology company with a mission to be the leading RNA editing company delivering precision therapies to patients with rare and common diseases.

Tasks

Support the synthesis of oligonucleotides on mouse and non-human primate (NHP) scale (Mermade Cytiva K&A) for research and pre-clinical use
Apply and develop processing workflows and procedures to enhance time efficiency and product quality
Run systematic reaction optimizations on automated DNA synthesizers
Perform conjugation reactions of small molecules with oligonucleotides
Document and report experimental results
Write standard operating procedures (SOPs)
Maintain a clean and safe working environment
Pro-actively communicate with other team members and colleagues within the company

Requirements

MSc in organic chemistry or related (or BSc with min. 2 years of industry experience)
Familiarity with oligonucleotide chemistry and previous work experience is considered a plus
Solid wet lab skills: pipetting manipulating liquids handling chemicals work in laminar flow hood etc.; familiarity with HPLC equipment is considered a plus familiarity with oligonucleotide synthesizers is a big plus
Hands-on approach and can-do attitude precision and attention to detail
Team player with excellent communication skills in spoken and written English German is a plus
A valid work permit for Germany is mandatory

Benefits

An exciting role in a promising high-impact research field.
The opportunity to contribute to the development of future medicines.
Work within a fast-growing startup that values innovation and scientific excellence.
Collaborate with a diverse enthusiastic and international team.
Be part of the ONE AIRNA culture.
Attractive compensation stock options and additional benefits.
The position involves working across both Germany and the US and intercultural exchange opportunities.

The position is based in Tübingen Germany.