Postdoctoral Associate Stanley Center

Broad Institute

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profile Job Location:

Cambridge, MA - USA

profile Monthly Salary: Not Disclosed
Posted on: 30+ days ago
Vacancies: 1 Vacancy

Job Summary

General information

Location
Cambridge MA
Ref #
43110
Job Family
Research
Workplace
On-Site
Date published
15-Oct-2025
Time Type
Full time

Description & Requirements

We are looking for a highly motivated Junior Postdoctoral Associate to join a dynamic team investigating the physiology of thalamic circuits in animal models of psychiatric disorders. The candidate is expected to have experience in vivo electrophysiology including local field potential (LFP) single-unit and multi-unit recordings to study how thalamocortical dysfunction contributes to sensory attentional cognitive and other behavioral abnormalities. The position provides an opportunity to integrate these approaches with complementary in vivo imaging techniques (e.g. calcium imaging GRAB sensors functional ultrasound or fMRI) and advanced data analysis to achieve a systems-level understanding of brain circuit function.


The Stanley Center and the Broad Instituteprovide a vibrant research environment with close links to MIT Harvard and the Harvard-affiliated hospitals across Boston. Being a member of our team will provide the opportunity for your contributions to be utilized and recognized across the vast global network of researchers in the fields of genomics and psychiatric disease research.

CHARACTERISTIC DUTIES
Perform in vivo electrophysiology recordings in rodent models including LFP single-unit and multi-unit recordings in thalamus and connected circuits of rodent models.
Implement optogenetic or chemogenetic manipulations to dissect circuit-specific mechanisms.
Analyze neural activity using advanced data processing approaches such as spike sorting spectral analysis connectivity metrics and state-space modeling.
Collaborate with team members to integrate electrophysiological findings with in vivo imaging methods including calcium imaging functional ultrasound (fUS) and fMRI.
Rodent colony maintenance and handling.
Prepare manuscripts and present findings at conferences.
Provide mentorship and training for graduate students technicians or junior researchers.

QUALIFICATIONS
Ph.D. in neurobiology neuroscience biomedical engineering or a related field.
Prior lab experience in in vivo electrophysiology (LFP single-unit multi-unit recordings).
Must be comfortable working with animals.
Proficiency in at least one scientific programming language (e.g. Python MATLAB R) for data analysis.

Outstanding personal initiative and communication skills and be able to work in a team.
Exceptional organizational and time management skills lab notebook practices and attention to detail.


Required Experience:

IC

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Key Skills

  • Virology
  • Bioinformatics
  • Genetics
  • R
  • Biochemistry
  • Cell Biology
  • Research Experience
  • Spectroscopy
  • Cell Culture
  • Molecular Biology
  • Microscopy
  • Research Laboratory Experience

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Broad Institute is a multidisciplinary community of researchers on a mission to improve human health.

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