Scientist, Biologics Production
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Job Location:
Gaithersburg, MD - USA
Monthly Salary:
$ 80653 - 120980
Posted on:
15-10-2025
Vacancies:
1 Vacancy
Job Summary
Scientist Biologics Production
Are you ready to be part of a dynamic team that is revolutionizing biologics production We are building a high-throughput automation-first engine to deliver complex biologicsincluding IgGs and multispecificsfaster at higher quality and at scale. As a Scientist in Biologics Production you will play a crucial role within an integrated team that spans mammalian expression purification and fit-for-purpose analytics. Your mission To compress DNA-to-material timelines for discovery programs and technology development. If you have the drive to innovate a collaborative mindset and the ability to communicate and deliver molecules and corresponding data packages this is the opportunity for you!
Accountabilities:
Production & Process Development
- Aid and execute in improving the sequence-to-material pipeline: transient CHO/HEK expression purification and QC assessment of IgGs VHH (/- Fc) and multispecifics using high-throughput workflows.
- Predictive analytical QC routes to inform purification groups and meet therapy area demand for decision-quality materials and technology development initiatives.
Purification Automation Analytics & Digital Operations
- Automated liquid-handling workflows in relation to biologics purification (monospecific and multispecific) and analytical stations (SEC-HPLC or UPLC CE-SDS).
- Embed data integrity and compliance across workflows via Genedata Biologics eLN and Smartsheet governance and training.
- Maintain in-process controls and release-for-use criteria in partnership with Analytics and Developability including SEC CE-SDS Endotoxin and HCP.
Cross-Functional Impact
- Partner closely with Protein Engineering and Novel Modalities (PENM) Assays/Profiling and Pharmacology (APP) and PS&A Analytics and Developability and collaborate with BPD Purification Process Sciences for scale-up readiness.
Essential Skills/Experience:
- B.S. in Biochemistry Bio/Chemical Engineering or closely related field.
- 2-4 or more years in biologics production and purification in biotech or pharma.
- Experience in mammalian expression and purification/QC (transient CHO or HEK-derived).
- Digital and compliance acumen with Genedata Biologics and eLN or Smartsheet-based governance.
Desirable Skills/Experience:
- Hands-on experience in industry setting with Hamilton liquid-handling platforms for protein purification and normalization.
- Coordination and planning of liquid handler usage and routine operation.
- Experience with Unchained Labs instruments for UV/Vis as well as sample data management and transfer into liquid handling platforms.
- Programming knowledge is a plus for this position.
At AstraZeneca we are driven by a shared vision to eliminate cancer as a cause of death. Our pioneering spirit fuels bold moves that transform the way cancer is treated truly improving patient outcomes. With one of the broadest Oncology pipelines in the industry we offer countless opportunities to work with novel drugs and discover whats next. Our collaborative environment empowers you to take smart risks challenge norms and learn from failures. Join us in applying science to studies using innovative approaches that shape the future of Oncology.
Ready to make an impact Apply now to join our team!
The annual base pay (or hourly rate of compensation) for this position ranges from $80653.60 - 120980.40 USD. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors including market location job-related knowledge skills and addition our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles) to receive a retirement contribution (hourly roles) and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program 401(k) plan; paid vacation and holidays; paid leaves; and health benefits including medical prescription drug dental and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an at-will position and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.
Date Posted
09-Oct-2025Closing Date
14-Nov-2025Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.
Key Skills
- Laboratory Experience
- Immunoassays
- Machine Learning
- Biochemistry
- Assays
- Research Experience
- Spectroscopy
- Research & Development
- cGMP
- Cell Culture
- Molecular Biology
- Data Analysis Skills
About Company
AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, ... View more
