Senior Software Engineer (DeveloperSDET)

Redwood City, CA - USA

Monthly Salary: Not Disclosed

Posted on: 30 days ago

Vacancies: 1 Vacancy

Job Summary

About Karius

Karius is a venture-backed life science startup that is transforming the way pathogens and other microbes are observed throughout the body. By unlocking the information present in microbial cell-free DNA were helping doctors quickly solve their most challenging cases providing industry partners with access to 1000s of biomarkers to accelerate clinical trials discovering new microbes and reducing patient suffering worldwide.

Position Summary

We are seeking a Senior Software Engineer (Developer / SDET hybrid) to design build and test the analytical software systems that power the Karius test. Our team develops AI-driven bioinformatics and data pipelines to deliver life-saving results in the highly complex infectious disease this role you will drive both system development and improvements in testability automation and validation across the software lifecycle. You will collaborate closely with other engineers bioinformaticians product managers and quality stakeholders to ensure our systems are robust reliable and compliant. Your work will span from writing production code to building test frameworks and validation tools - directly contributing to the accuracy scalability and trustworthiness of the Karius platform and ultimately helping physicians treat patients more effectively.

Why Should You Join Us

Karius aims to conquer infectious diseases through innovations around genomic sequencing and machine learning. The companys platform is already delivering unprecedented insights into the microbial landscape providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood and helping industry accelerate the development of therapeutic solutions. The Karius test we provide today is one of the most advanced solutions available to physicians who aim to deliver better care to many otherwise ineffectively treated patients. Our test is the result of some incredible work done by our scientists statisticians engineers and physicians all driven by the same mission. You as part of the Karius team will be able to see how directly your work has a life-changing impact on people and at scale.

Reports to: Director Analytical Systems & Data Insights

Location: Redwood City CA (Hybrid)

Primary Responsibilities

Software Development (Back-End Focus) - Drive the design and implementation of production software systems that power Kariuss analytical pipelines.

Design build and maintain back-end software systems spanning analytical pipelines APIs data processing services and supporting infrastructure.

Implement scalable reliable and secure services for ingesting storing and processing large volumes of genomic data.

Collaborate with bioinformaticians on integrating algorithms and analytical pipelines into production systems.

Contribute to architecture and design reviews emphasizing performance reliability and maintainability.

Contribute to peer code reviews design discussions and sprint planning as part of the team.

Software Testing - Build and sustain the frameworks and processes that ensure our systems meet the highest standards of reliability performance and compliance.

Develop and maintain test automation frameworks and tools (e.g. Pytest Postman custom command-line tooling/scripts) to ensure comprehensive coverage of unit integration regression and system-level testing.

Translate requirements and specifications into well-structured test cases and test plans ensuring traceability between requirements risks and test cases using modern tools and processes.

Support the execution and documentation of verification and validation (V&V) activities ensuring compliance with regulated software development practices.

Advocate for testability and quality throughout the software lifecycle helping shape designs that are easier to validate and maintain.

Whats Fun About the Job

Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that comes a wave of new and incredible challenges and opportunities. To deliver on that value you will be tapping into some of the most advanced technologies architecting and innovating where the current solutions simply dont suffice. You will get to see how much your work really matters.

Travel: (1x week minimum) Onsite for all team meetings.

Physical Requirements

Subject to extended periods of sitting and/or standing vision to monitor and moderate noise levels. Work is generally performed in an office environment.

Position Requirements

BS or MS degree in Computer Science Software Engineering Electrical Engineering Bioengineering or a related technical field involving algorithms or coding (e.g. physics or mathematics).

5 years of experience designing developing and maintaining production software systems (Python preferred) ideally with experience in regulated environments (e.g. healthcare life sciences).

Experience with cloud platforms (e.g. AWS Azure GCP) and developing distributed cloud-based systems using modern technologies and flows (e.g. Docker Kubernetes Git/GitHub CI/CD Kafka GraphQL).

Experience across the full software development lifecycle including project management requirements traceability and test automation using Python and modern frameworks (e.g. Pytest Postman Playwright Selenium).

Familiarity with bioinformatics tools and genomic data formats is a strong plus.

Familiarity with regulations pertaining to IVD and/or LDT development (e.g. 21 CFR Part 11 21 CFR Part 820 CAP/CLIA NYS DOH) and related standards (e.g. IEC 62304 ISO 13485 ISO 14971) is a strong plus.

Personal Qualifications

Passionate purpose-driven and excited about Karius mission.

Strong organizational and time management abilities.

Demonstrated ability to tackle complex problems.

Ability to work independently but also be an excellent team player.

A role model for Karius culture and values with a commitment to integrity quality and excellence.

Disclaimer

The above job description is intended to describe the general nature and level of work being performed by individuals assigned to this position. It is not intended to be an exhaustive list of all duties responsibilities and skills required. Responsibilities and duties may change or be adjusted to meet the needs of the company and additional duties may be assigned as necessary. The job description is subject to change at any time at the discretion of Karius.

Equal Opportunity Employer

At Karius we value a diverse and inclusive workplace and provide equal employment opportunities for all applicants and employees and are committed to honor and invest in the full diversity of people in our hiring recruiting and development of employees across the Company. All qualified applicants for employment are encouraged to apply and will be considered without regard to an individuals race color sex gender identity and gender expression (including transgender individuals who are transitioning have transitioned or are perceived to be transitioning to the gender with which they identify) religion age national origin or ancestry citizenship physical or mental disability medical condition family care status marital status domestic partner status sexual orientation genetic information military or veteran status or any other basis protected by federal state or local laws. If you are unable to submit your application due to a disability please contact us at and we will accommodate qualified individuals with disabilities.

$137725 - $206587 a year

Required Experience:

Senior IC

About KariusKarius is a venture-backed life science startup that is transforming the way pathogens and other microbes are observed throughout the body. By unlocking the information present in microbial cell-free DNA were helping doctors quickly solve their most challenging cases providing industry p...