Postdoctoral Fellow P Znamenskiy lab

Salary for this Role:

From 45500 with benefits subject to skills and experience

Job Title:

Reports to:

Closing Date:

Job Description:

Postdoctoral Fellow - P Znamenskiy lab

Details of the role:

Reporting to: Petr Znamenskiy Group Leader

Contact term: This is a full-time fixed term 4-year position on Crick terms and conditions of employment.

About us

The Francis Crick Institute is Europes largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent diagnose and treat illnesses such as cancer heart disease infectious diseases and neurodegenerative conditions.

The Crick is a place for collaboration innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure cutting-edge facilities and a creative and curious culture. Weve removed traditional boundaries of departments divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.

About the role

The Znamenskiy lab studies the relationship between the in vivo function synaptic organization and molecular identity of cortical neurons. We aim to understand how connections between different neuronal cell types are organized and how this organization enables the computations they perform.

Mechanistic understanding of how networks of neurons carry out neural computations requires detailed knowledge of their underlying synaptic connectivity. However traditional methods for reconstructing synaptic connections are extremely laborious and typically limited to mapping connections between nearby neurons. To overcome this we have recently developed Barcoded Rabies In Situ Connectomics (BRISC) a new method that uses libraries of rabies viruses expressing random mRNA barcodes for a high-throughput circuit tracing.

BRISC has opened exciting new avenues for research aiming to understand how connectivity rules across different cell types and areas of the brain support neural computations and how they are altered in disease models. Multiple postdoctoral projects are available depending on your area of interest including:

• Exploring the organisational principle of long-range cortico-cortical communications by mapping connections between different areas at the single cell level.

• Identifying wiring defects in mouse models of neurological and psychiatric disease.

• Relating gene expression patterns of single neurons to their synaptic connectivity.

If you have strong data analysis experience and a PHD in Neuroscience or a related field we would love to hear from you.

About you

You will have:

(Minimum criteria *)

• PhD in Neuroscience or a related field or in the final stages of PhD submission *

• Strong track record of scientific contribution as evidenced by publications preprints or submitted manuscripts *

• Experience in coding in Python or MATLAB *

Please see the full job description here.

See more information about the lab here.

About Working at the Crick

Our values

Everyone who works at the Crick has a valuable role to play in advancing the Cricks mission and shaping our culture!

• We arebold. We make space for creative dynamic and imaginative ideas and approaches. Were not afraid to do things differently.

• We areopen. Were highly collaborative and interactive and make sure our activities are visible to the outside world.

• We arecollegial. We show respect for one another work cooperatively and support the wider community.

At the Francis Crick Institute we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued respected and empowered to succeed regardless of their background identity or personal circumstances. We actively encourage applications from individuals of all genders ethnicities abilities and experiences. Weare aDisability Confident: Committedemployer andwant to ensure that everyone can apply and be part of our recruitment processes and sowellmake reasonable adjustments if you need them - just let us know when you apply. If you needassistancewith applying (i.e. would like to apply by phone or post)please email:

Find out more about life at the Crick.

What will you receive

At the Francis Crick Institute we value our team members and are proud to offer an extensive range of benefits to support their well-being and development:

• Generous Leave: 28 days of annual leave plus three additional days over Christmas and bank holidays.

• Pension Scheme: Defined contribution pension with employer contributions of up to 16%.

• Health & Well-being:

• 24/7 GP consultation services.

• Occupational health services and mental health support programs.

• Eye care vouchers and discounted healthcare plans.

• Work-Life Balance:

• Back-up care for dependents.

• Childcare support allowance.

• Annual leave purchase options.

• Crick Networks offering diverse groups support community and inclusive social events.

• Perks:

• Discounted gym memberships bike-to-work scheme and shopping discounts.

• Subsidised on-site restaurant and social spaces for team interaction.

Please note you must meet the essential criteria listed within the Role Profile to have your application reviewed.

We reserve the right to withdraw this advert at any given time due to the number of applications received.