Postdoctoral Fellow-MSH
Postdoctoral Fellow-MSH
Employer Active
Job Alert
You will be updated with latest job alerts via email
Share
Job Alert
You will be updated with latest job alerts via email
Not Disclosed
Salary Not Disclosed
1 Vacancy
Job Description
Details of Research Project: Postdoctoral fellowship focused on projects to reduce the burden of global cardiovascular disease by designing and performing randomized clinical trials. The aim of the research team is to reduce the future risk of obesity heart attacks strokes and type 2 diabetes as well as address atrial fibrillation and other common cardiovascular comorbidities. To ensure this the fellow will leverage data from various large randomized clinical trials that are being designed/ongoing in the Institution and will deepen his knowledge on research methodology cardiovascular clinical trials design and manuscript preparation for high-impact journals. The two main ongoing trials are the PRECAD and the reintervention trial for the FAMILIA cohort (FAMILIA-REUNION) in which the fellow will play an active role in the design organization and scientific curation.
Responsibilities
Technical Duties: (include any protocols)
- Assisting in the design and follow-up of randomized clinical trials.
- Assessing the health promotion interventions.
- Guaranteeing data protection and compliance with data protection and transfer laws.
- Devising plans for and assessing the participants involved in the study.
- Managing research data; helping to reply to queries related to the institutions financing the research projects requesting program updates.
- Preparing publications for submission to high-impact journals.
- Organizing and giving presentations.
- Collaborating in subsidy applications for the different projects
Qualifications
Educational and other Requirements for the position:
The position requires a candidate with a minimum of four years of research experience ideally in clinical or translational cardiovascular research. A strong background in clinical trial coordination advanced imaging techniques and data analysis is essential. Familiarity with LDL-lowering therapies and cardiovascular prevention strategies will be highly valued. The candidate should also demonstrate competence in scientific writing and communication and have experience working in interdisciplinary and international research environments. Training in Good Clinical Practice (GCP) and the ability to manage multi-center studies are considered important assets for successful performance in this role.
Experience Required:
Applicants must have at least four years of hands-on experience in biomedical or clinical research preferably within the field of cardiovascular prevention or lipid metabolism. Experience with electronic data capture systems regulatory documentation and image-based analysis of atherosclerosis (e.g. 3D vascular ultrasound) will be critical. The candidate should also be comfortable working in collaborative international teams and coordinating with multiple study sites. Previous publications leadership in sub-studies or participation in multicenter research consortia will be considered strong indicators of preparedness for this position
Goals/Outcomes of the Research Project:
The PRECAD clinical trial aims to assess the long-term benefits of early intensive LDL-cholesterol lowering in young adults at high cardiovascular risk. The primary goal is to compare the progression of atherosclerotic plaque volume over five years using 3D vascular ultrasound between patients receiving standard care and those undergoing intensive intervention including inclisiran. Secondary objectives include evaluating major cardiovascular events changes in lipid profiles and treatment adherence. Exploratory analyses will focus on biomarkers cumulative LDL exposure and subgroup effects (e.g. familial hypercholesterolemia). This research seeks to inform future clinical guidelines and shift preventive strategies to younger populations.
The reintervention in the FAMILIA cohort (FAMILIA-REUNION) is expected to improve health literacy and habits in the short and medium the longer follow-up objective endpoints such as blood biomarkers will be assessed. The researcher will engage in other projects proposed by his supervisor as well.
Employment Type
Full-Time
