Research Service Professional (iPSC Editing Specialist)
Research Service Professional (iPSC Editing Specialist)
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Job Description
University of Colorado Anschutz Medical Campus
Department:Pharmacology / Functional Genomics Facility
Job Title:Research Service Professional (iPSC Editing Specialist)
Position # Requisition # 37909
Job Summary:
We are urgently seeking a dynamic Research Scientist to lead a high-priority project focused on precision editing of induced pluripotent stem cells (iPSCs). This role is central to advancing our capabilities in disease modeling and therapeutic discovery in the field of Down Syndrome. The ideal candidate will have deep expertise in genome editing (e.g. CRISPR) stem cell biology and functional genomics and will drive innovation in editing strategies and platform development.
This is a pivotal opportunity to shape a transformative research initiative with broad translational impact. Join us in pushing the boundaries of stem cell engineering.
Key Responsibilities / Duties: (There should be 10 duties and duties should be grouped under a section header collectively; the section headers add up to 100%)
iPSC editing and analysis
iPSC culture
CRISPR-mediated gene editing in iPSC lines
Perform RNA DNA and protein extraction and quality control as well as other various molecular biology-related assays (qPCR dPCR western blot amplicon sequencing NGS library preparation etc.)
Inventory storage and management of biospecimens; associated record keeping
Manage edited iPSC inventory in collaboration with the Human Trisome Project biobank Crnic Institute clinical trials and associated investigations
Edited iPSC record keeping
Collaborate with researchers from other programs within the Crnic Institute (clinical experimental models data teams) to accomplish project goals and share research results
Assist senior staff in the design execution and evaluation of research investigations including literature reviews performing experiments and pilots data integration and analysis
Foundational lab maintenance responsibilities
Assist with various laboratory and clinical support operations such as autoclaving inventories ordering supplies and hazardous materials management.
Prepare lab for daily operations including stocking materials equipment safety cleanliness and related areas
Work Location:
Onsite this role is expected to work onsite and is located in Aurora CO.
Why Join Us:
Join a mission-driven team at the forefront of precision medicine and genetic research. The Functional Genomics Shared Resource (FGSR) a leading core facility specializing in gene function analysis has partnered with the Linda Crnic Institute for Down Syndromethe largest academic hub for Down syndrome research globally. Together we are advancing transformative science that directly improves health outcomes for individuals with Down syndrome.
As part of our iPSC team youll contribute to cutting-edge work in gene editing and functional validation of iPSC lines helping build a gene-corrected iPSC panel that will serve as a foundational resource for future discoveries. Youll gain hands-on experience with CRISPR-based heterozygous gene editing technology and a wide array of functional assaysall while working in a collaborative intellectually stimulating environment.
Were looking for detail-oriented motivated and enthusiastic Laboratory Science Professionals who are passionate about making a real-world impact through science. If you thrive in fast-paced research setting and want to be part of a team that values innovation precision and purposethis is your opportunity to make a difference.
Why work for the University
We haveAMAZINGbenefits and offerexceptional amounts of holiday vacation and sick leave! The University of Colorado offers an excellent benefits package including:
Medical: Multiple plan options
Dental: Multiple plan options
Additional Insurance: Disability Life Vision
Retirement 401(a) Plan: Employer contributes 10% of your gross pay
Paid Time Off: Accruals over the year
Vacation Days: 22/year (maximum accrual 352 hours)
Sick Days: 15/year (unlimited maximum accrual)
Holiday Days: 10/year
Tuition Benefit: Employees have access to this benefit on all CU campuses
ECO Pass: Reduced rate RTD Bus and light rail service
There are many additional perks & programs with the CU Advantage.
Qualifications:
Minimum Qualifications:
A bachelors degree in biology molecular biology chemistry genetics or a directly related field from an accredited institution
One (1) year of professional-level experience
Preferred Qualifications:
A masters degree in biology molecular biology chemistry genetics or a directly related field from an accredited institution
Two (2) years of professional-level experience
Individuals with advanced degree and research experience are encouraged to apply
Experience with iPSC maintenance differentiation and experimentation
Experience in CRISPR technology
Experience independently researching synthesizing and presenting novel and assigned topics.
Experience in training all ability levels (e.g. interns colleagues) in sample processing procedures.
Competencies: Knowledge Skills and Abilities
Ability to communicate effectively both in writing and orally.
Ability to establish and maintain effective working relationships with employees at all levels throughout the institution.
Ability to work with iPSC using established protocols.
Flexibility and adaptability to schedule changes including occasional night and weekend hours.
Knowledge of aseptic technique and standard cell culture practices
Must be hard-working independent yet team-oriented flexible and able to communicate effectively.
Self-motivated and highly organized with demonstrated project planning and management skills in an academic research setting.
Strong qualitative analysis skills
Strong word processing skills particularly with advanced Excel functions
Ability to manage the lab
Demonstrated ability to plan present and conduct independent experiments.
Willingness and working knowledge to assist the clinical research team and animal research team as needed.
Familiarity with genomic gene expression proteomic and metabolomic platforms.
How to Apply:
For full consideration please submit the following document(s):
1. A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position
2. Curriculum vitae / Resume
3. Three to five professional references including name address phone number (mobile number if appropriate) and email address
Questions should be directed to: Molishree Joshi
Screening of Applications Begins:
Immediately and continues until position is filled.
Anticipated Pay Range:
Equal Employment Opportunity Statement:
The starting salary range (or hiring range) for this position has been established as HIRING RANGE ($50357 - $64054).
The above salary range (or hiring range) represents the Universitys good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation depending on the level.
Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave health plans and retirement contributions that add to your bottom line.
ADA Statement:
The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act please contact the Human Resources ADA Coordinator at .
Background Check Statement:
The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty staff students and visitors. To assist in achieving that goal we conduct background investigations for all prospective employees.
Vaccination Statement:
CU Anschutz strongly encourages vaccination against the COVID-19 virus and othervaccine preventable diseases. If you work visit or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work visit or volunteer addition if you work in certain research areas or perform certain safety sensitive job duties you must enroll in theoccupational health medical surveillance program.
Required Experience:
IC
Employment Type
Full-Time
