Staff Bioinformatics Scientist

Guardant Health

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profile Job Location:

Palo Alto, CA - USA

profile Monthly Salary: Not Disclosed
Posted on: 30+ days ago
Vacancies: 1 Vacancy

Job Summary

The position is in the bioinformatics group and will work on the development of computational models for both the screening products (Shield) and the oncology products (e.g. Guardant360). The major responsibilities are to

  • Develop prototype and analyze performance of novel statistical/machine learning models to further improve early cancer detection minimal residual disease detection longitudinal monitoring of treatment response and cancer-signal-origin prediction

  • Work closely with other teams to develop new technologies both through hands-on work and providing ideas to team members

  • Identify relevant external genomic epigenomic and proteomic data sources and integrate with internal data to improve product performance and suggest new product features

  • Participate in brainstorming sessions maintain a highly productive and motivating work environment

  • Work cross functionally with other teams to provide insight and feedback on projects

  • Provide written documentation and specifications for transparency and reproducibility

  • The preferred location for this position is either Palo Alto or San Diego.


Qualifications :

  • Dedicated to make a difference in a rapid-paced collaborative startup-like environment

  • Ph.D. in computational biology/bioinformatics genomics machine learning or related field and a minimum of 8 years related experience

  • Experienced with statistical models for genomic/epigenomic data

  • Proficiency with a high-level scripting language (Python/R; Python preferred)

  • Experienced in visualization of complex experiments to derive biological insights

  • Proficiency creating interactive tools and dashboards (streamlit CLI tools etc.)

  • Proficiency creating and maintaining large data lakes and automated processing of constantly incoming data

Preferred

  • Cancer biology and/or epigenetics background

  • Experience in analyzing public genomic/epigenomic datasets (e.g. TCGA ENCODE)

  • Proficiency with Linux command-line and version control tools (git and GitHub)

  • Ability to build reproducible and well written code (or packages) for data analysis

  • Familiar with high-performance computing infrastructures (e.g. SGE AWS Spark)


Additional Information :

Hybrid Work Model: At Guardant Health we have defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays Tuesdays and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.

The US base salary range for this full-time position is $148500 to $204210. The range does not include benefits and if applicable bonus commission or equity. The range displayed reflects the minimum and maximum target for new hire salaries across all US locations for the posted role with the exception of any locations specifically referenced below (if any).

For positions based in Palo Alto CA or Redwood City CA the base salary range for this full-time position is $174700 to $240250. The range does not include benefits and if applicable bonus commission or equity.

Within the range individual pay is determined by work location and additional factors including but not limited to job-related skills experience and relevant education or training. If you are selected to move forward the recruiting team will provide details specific to the factors above.

Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however there may be exposure to high noise levels fumes and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities long-term conditions mental health conditions or sincerely held religious beliefs. If you need support please reach out to 

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity national origin or protected veteran status and will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.

To learn more about the information collected when you apply for a position at Guardant Health Inc. and how it is used please review our Privacy Notice for Job Applicants.

Please visit our career page at:  Work :

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Employment Type :

Full-time

The position is in the bioinformatics group and will work on the development of computational models for both the screening products (Shield) and the oncology products (e.g. Guardant360). The major responsibilities are toDevelop prototype and analyze performance of novel statistical/machine learning...
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Key Skills

  • Laboratory Experience
  • Bioinformatics
  • Biochemistry
  • Utility Locating
  • Assays
  • Research Experience
  • Next Generation Sequencing
  • Sensors
  • Signal Processing
  • Matlab
  • Research & Development
  • Molecular Biology

About Company

Guardant Health is a leading precision oncology company focused on helping conquer cancer globally through use of its proprietary tests, vast data sets and advanced analytics. The Guardant Health oncology platform leverages capabilities to drive commercial adoption, improve patient cl ... View more

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