Sets up and performs routine and established lab procedures in support of lab goals grant commitments i.e. assays cell/tissue culture animal studies etc. Monitors results reports unusual outcomes and suggests modifications. Collects enters and summarizes data. Assists in the maintenance of lab equipment and supplies. Performs basic statistical data analysis; prepares tables/charts/graphs and assists in organizing data. Presents at research laboratory meetings and contributes to writing of manuscripts. Works under supervision and may perform some assignments independently as discussed and approved by Principal Investigator.
The current project is to bioinformatically investigate the molecular evolution of clonal hematopoiesis in breast cancer and link this information to the rich outcomes in clinical cohorts at the Mayo Clinic. The job requires bioinformatic database web authoring and programming skills for this 2-year project. The overall objective is to accurately call somatic mutations in large cohorts based on our previously published LiFT filter and to link cancer progression and outcome data to mutation status.
The position will drive data integration approaches from different sources such as whole genome sequencing single cell omics bulk RNA-seq and ATAC-Seq and DNA and develop analysis pipelines. The post-holder will establish new bioinformatics data analysis methods as required and communicate developments in the field of genomics and hematology to the local research community. The post-holder will be responsible for management of good data storage practices adherence to relevant regulation (for example human data) methods development SOPs budget management and appropriate record keeping. The post-holder provide in-depth bioinformatics-based technical support to members of the Kirschner lab.
Requires bachelors degree in biology chemistry other relevant science or an associates degree with 6 years of relevant laboratory experience. Must exhibit a solid understanding of lab techniques equipment and safety. Must have the ability to organize and carry out laboratory techniques independently and in a team setting. Experience with basic data analysis is required. This position requires demonstrated writing skills.
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