Associate Scientist Biology

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profile Job Location:

Cambridge - USA

profile Monthly Salary: Not Disclosed
Posted on: 30+ days ago
Vacancies: 1 Vacancy

Job Summary

How will your role help us transform hope into reality

Research identify and validate novel oncology targets and small molecule drug discovery utilizing knowledge of bioengineering to develop and conduct cellular assays to support Blueprint Medicines novel drug discovery efforts.

What will you do

  1. Manages and QC routines assays performed at CRO and upload data to our server. (15%)
  2. Optimize and employ cellular and molecular assays such as Western blotting Elisa and immunofluorescence-based assays to elucidate mechanistic biology of potential drug targets and mechanism of action of small molecules. (20%)
  3. Present research findings at team meetings. (5%)
  4. Maintain our automation platform and is the point of contact with the vendor when needed (such as major issues to be fixed or implementation of new updates). (15%)
  5. Design and development of automation methods for biological assays for several projects. Teach colleagues how to use those methods and troubleshoot when necessary. (15%)
  6. Cell culture Maintenance. (10%)
  7. Run routine assays when needed. (10%)
  8. Maintain detailed and critical experimental data records that are published in ELN according to industry compliance. (10%)

What minimum qualifications do we require

Masters degree in Bioengineering Biomedical Engineering or a closely related biological or life sciences field (or foreign equivalent degree) plus 1 year of experience in biological research for oncology drug development.

Experience which may be gained concurrently must include:

  • 1 year of experience in maintaining expanding and freezing cell lines.
  • 1 year of experience with running routine assays such as Alphalisa pERK and proliferation assays.
  • 1 year of experience in using and programming liquid handlers such as Bravo Biomek Integra Assist Plus and D300.
  • 1 year of experience in analyzing cell research data and presenting it to the team.
  • 1 year of experience in analyzing and presenting scientific research papers.
  • 1 year of experience in maintaining detailed ELN to ensure data reproducibility.

* This position is part of Blueprint Medicines employee referral program and is eligible for an employee referral incentive bonus.

Why Blueprint

At Blueprint Medicines we achieve impactful results because of our global crew of compassionate innovators the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights which drives our success.

This is the place where the extraordinary becomes reality and you could be part of it.

Patients are waiting. Are you ready to make the leap

Equal Employment Opportunity

At Blueprint Medicines wefoster an environment of fair treatment and full participationforall of our employees as we navigate complex challenges in pursuing our mission to improve the lives of patients. We celebrate our unique differences and varied career and life experiences so that we can sustain our diverse culture and ensure everyone feels accepted. We arecommitted to non-discrimination equal employment opportunity as well as an inclusive recruitment process. We consider all qualified applicants based on merit and without regard to race color sex gender identity sexual orientation age religion national origin ancestry ethnicity disability veteran status genetic information or any other characteristic protected under applicable federal or state law.


We will make reasonable accommodations absent undue hardshipforqualified individuals with known disabilities. If you are an individual with a disability in need of an accommodation with theapplicationor recruiting process please reach out to We are also an E-Verify information please see ourEEOPolicy Statement theE-Verify Participation Poster theRight to Work Poster and theEEOKnow Your Rights Poster.

Blueprint Medicines a Sanofi company is a global biopharmaceutical company that invents life-changing medicines. We seek to improve and extend patients lives by solving important medical problems with a focus on allergy/inflammation and oncology/hematology. Our approach begins by targeting the root causes of disease using deep scientific knowledge in our core focus areas and drug discovery expertise across multiple therapeutic modalities. We have a track record of success with two approved medicines including AYVAKIT/AYVAKYT (avapritinib) which we are bringing to patients with SM in . Leveraging our established research development and commercial capability and infrastructure we aim to significantly scale our impact by advancing a broad pipeline of programs ranging from early science to advanced clinical trials in mast cell diseases and solid tumors. For more information visitand follow us onX(formerly Twitter; @BlueprintMeds) andLinkedIn.

Requisition #: 25-604

#LI-DNI


Required Experience:

IC

How will your role help us transform hope into realityResearch identify and validate novel oncology targets and small molecule drug discovery utilizing knowledge of bioengineering to develop and conduct cellular assays to support Blueprint Medicines novel drug discovery efforts.What will you doManag...
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Key Skills

  • Laboratory Experience
  • ELISA
  • Immunoassays
  • Transfection
  • Mammalian Cell Culture
  • Suspension Experience
  • Biochemistry
  • Assays
  • cGMP
  • Cell Culture
  • Molecular Biology
  • Flow Cytometry