Employer Active
Job Alert
You will be updated with latest job alerts via emailJob Alert
You will be updated with latest job alerts via emailNot Disclosed
Salary Not Disclosed
1 Vacancy
The research focuses on understanding and targeting epigenetic and splicing factors in high-risk neuroblastoma. This work is highly mechanistic and translational leveraging cutting-edge genetic epigenomic and pharmacologic tools in patient-derived xenografts and genetically engineered mouse models to inform better therapies.
Key Responsibilities
Design and conduct experiments investigating the role of epigenetic regulators in regulating therapy resistance.
Utilize molecular cellular and biochemical techniques including CRISPR RNA-seq CUT&RUN ATAC-seq HiC flow cytometry and 3D tumor modeling.
Analyze how epigenetic modulation alters chromatin states and cell state transitions.
Evaluate preclinical efficacy of molecular glue drugs in combination with standard therapies.
Collaborate within a multidisciplinary team including cancer biologists and clinicians.
Present findings at national and international meetings and contribute to manuscript preparation and grant proposals.
Qualifications
A Ph.D. (or nearing completion) in molecular biology cancer biology biochemistry developmental biology immunology or related fields.
Strong background in epigenetics transcriptional regulation or chromatin biology is highly desirable.
Experience with mouse models genome editing or next-generation sequencing is a plus.
Excellent communication skills critical thinking and a collaborative mindset.
A strong publication record demonstrating scientific rigor and productivity.
No Search Firms
St. Jude Childrens Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.
Required Experience:
IC
Full-Time