Position Details: Our client a world-leading Pharmaceutical Company in Andover MA is currently looking for a Proteomics Scientist to join their expanding team.
Job Title: Proteomics Scientist / Mass Spectrometry Duration: 12 months contract extendable up to 48 months
Location: Andover MA
Note: The client has the
right-to-hire you as a permanent employee at any time during or after the end of the contract.
You may participate in the company group
medical insurance plan
Job Description: Proteomics Bench Scientist
Summary:
The Proteomics Bench Scientist will support Pfizer to develop and optimize mass spectrometry-based proteomics workflows.
This role involves sample preparation from cell lines and other matrices high-resolution MS analysis (Orbitrap timsTOF) and data processing using bioinformatics tools.
The ideal candidate has experience with TMT or DIA quantification LC-MS workflows and collaborative method development.
An MSc with 5 years of experience is required PhD candidates are preferred.
Responsibilities:
Responsible for developing proteomics workflows using advanced high-resolution mass spectrometry techniques
Development and optimization of sample preparation methods from cell lines and other matrices for mass spectrometry analysis and data processing with various bioinformatics tools
Applying knowledge of proteomics workflows to develop and implement optimal strategies for the preparation and analysis of cellular samples
Working collaboratively with experts in the team to advance innovative proteomics strategies
Employing different bioinformatics tools for data analysis and fitting
Consistent record keeping using an electronic lab notebook (ELN)
Daily interaction with managers and 3-4 colleagues in the cross-functional team for method development laboratory work prioritization experiment planning and execution
Participation in bi-weekly group meetings and other team meetings and discussions as relevant
Minimum Qualifications:
with at least 5 years OR PhD with 0 years in a relevant scientific field with a documented experience in proteomics and mass-spectrometry
Advanced knowledge and documented expertise with mass-spectrometry based proteomics approaches: label- or label-free quantification (TMT or DIA)
Experience with high-resolution mass-spectrometry instruments such as Orbitraps and timsTOF
Experience with sample preparation based on enrichment (incl. affinity purification) and universal protein extraction
Bioinformatics skills relevant for mass-spec data search statistical analysis and visualization
Expertise in LC-MS based proteomics.
Preferable Qualifications:
Experience with membrane protein analysis and/or cell surface proteomics
Knowledge of cell culture techniques and experience conducting cell-based assays
Experience with cell culture and cell manipulation is a plus
Location/Schedule:
Fully onsite role in Andover MA
Monday - Friday: 40 hours per week role