Temp Scientist I, New Discovery & Platform
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Job Location:
Redwood City - USA
Monthly Salary:
Not Disclosed
Posted on:
05-09-2025
Vacancies:
1 Vacancy
Job Summary
Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The companys R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team you will join other outstanding Revolutionariesin a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
The Opportunity:
We are seeking a curious and dedicated Scientist to join the New Discovery & Platform team within Discovery Sciences. The successful candidate will support early-stage discovery efforts aimed at interrogating new targets deploying current oncology assay technologies and developing new technology platforms to advance drug discovery.
This primarily lab-focused role will contribute at the bench by developing lysate-based assays supporting pooled screening and advancing new assay addition to strong experimental skills we seek a scientist who bridges chemistry and biology with a track record of creative innovative assay development to expand our discovery capabilities.
Responsibilities
Develop and apply methods for screening proteinprotein interactions (e.g. MSD BLI) to assess target engagement in physiologically relevant contexts.
Apply and expand biochemical and biophysical assay platforms including TR-FRET fluorescence polarization (FP) surface plasmon resonance (SPR) biolayer interferometry (BLI) and mass spectrometry.
Design develop and execute pooled screening experiments (e.g. DEL display technologies such as mRNA or yeast display).
Perform chemical or protein conjugation/labeling to support assay development target characterization and platform innovation.
Interrogate new therapeutic targets while deploying current oncology assay technologies and contributing to new technology development.
Optimize troubleshoot and analyze assays to support early-stage discovery projects.
Collaborate closely with internal partners to integrate experimental outcomes into broader discovery strategies.
Maintain accurate timely and detailed documentation of experiments and findings.
Support automation workflows and contribute to data analysis pipelines for high-throughput studies.
Required Skills Experience and Education
PhD in Chemical Biology Biochemistry Biophysics or related field (03 years of relevant industry or postdoctoral experience).
Evidence of bridging chemistry and biology with a demonstrated track record of innovative assay development.
Strong foundation in biochemical and biophysical methods for proteinligand interactions proteinprotein interactions and enzymatic activity measurement.
Hands-on experience with target engagement assays TR-FRET FP SPR BLI mass spectrometry pooled screening approaches (e.g. DEL mRNA display yeast display) and/or chemical/protein conjugation or labeling.
Proficiency in data analysis statistical interpretation and experimental design.
Demonstrated ability to excel in a primarily lab-focused environment with precision and attention to detail.
Excellent problem-solving skills adaptability and a collaborative mindset.
Preferred Skills:
Familiarity with laboratory automation systems and high-throughput workflows.
Experience with large dataset handling and visualization tools (e.g. Genedata Spotfire KNIME Vortex).
Detail-oriented with the ability to manage multiple priorities in a dynamic setting.
This is a contract position that will be employed through a third-party recruiting agency. The agency will provide the pay range which will be based on several factors including job-related skills experience market conditions and relevant education or training.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race color religion gender sexual orientation gender identity/expression national origin/ancestry age disability marital status medical condition and veteran status.
Revolution Medicines takes the protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect process and use any personal data that you provide to us in accordance with ourCCPA additional information please contact. #LI-Hybrid #LI-AP1
Key Skills
- Laboratory Experience
- Immunoassays
- Machine Learning
- Biochemistry
- Assays
- Research Experience
- Spectroscopy
- Research & Development
- cGMP
- Cell Culture
- Molecular Biology
- Data Analysis Skills
