Senior Scientist, BioScience, In-vitro Discovery
Senior Scientist, BioScience, In-vitro Discovery
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$ 108473 - 162710
1 Vacancy
Job Description
Senior Scientist BioScience In-vitro Discovery
Are you driven by the desire to discover and deliver life-changing medicines Do you have expertise in Biologics Engineering and want to make a significant impact in a company that transforms scientific ideas into reality AstraZeneca is looking for a passionate individual to join our team and contribute to the development of groundbreaking medicines!
Accountabilities
As a Senior Scientist you will play a pivotal role in advancing our biologics pipeline. You will independently design and execute discovery campaigns using phage and yeast-display technologies. Your responsibilities will include recovering yeast plasmids preparing samples for NGS data generation analyzing NGS data with software like Geneious Biologics and selecting hit lists for antibody production. You will contribute to technology platform builds streamline discovery workflows and present data as a lead scientist in multidisciplinary project teams. Collaboration across multiple groups in a matrixed environment is essential.
Essential Skills/Experience
- A PhD or equivalent experience in Molecular Biology Biochemistry Immunology with 0-6 years of post-doctoral experience in a relevant research area a Masters degree in a related field with 2 years of relevant laboratory experience or a Bachelors degree in Molecular Biology Biochemistry Immunology or related disciplines with 5 years of laboratory experience. Industry experience is a plus but not required.
- Extensive and current hands-on experience with phage and yeast-display technology for antibody discovery.
- Proven hands-on experience with NGS data generation (sample prepping) and sequence analysis.
- Data science and/or coding (python) skills highly desirable.
- Experience in high-throughput cloning DNA sequence analysis protein expression and purification ELISA flow cytometry and tissue culture.
- Ability to work independently and in a team setting.
- Self-motivated diligent and flexible in accommodating shifting priorities.
- Strong communication and interpersonal skills both oral and written with supervisor team and various cross-functional project team members.
- Maintain accurate and well-organized laboratory records including worksheets lab notebooks inventories and databases.
Desirable Skills/Experience
- Experience working with various antibody formats including VHH scFv and Fab.
- Familiarity with handling large datasets; data science skills are a plus.
- Transfection/electroporation culturing and expansion of mammalian cells.
- Experience with ELISA MSD cytotox and biolayer interferometry binding assays highly desirable.
- Experience with electronic notebook keeping and data entry using Gene Data Biologics.
AstraZeneca offers an empowering environment where you can act swiftly on smart risks. Our dynamic approach keeps us ahead in the fast-paced Oncology field. We encourage fearless decision-making and constructive challenges while always following scientific evidence. With one of the broadest Oncology pipelines in the industry youll have the opportunity to work with novel drugs and make bold moves that transform cancer treatment.
Apply now to join our team at AstraZeneca!
The annual base pay for this position ranges from $108473.60 - 162710.40. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime pay offered may vary depending on multiple individualized factors including market location job-related knowledge skills and addition our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles)to receive a retirement contribution (hourly roles) and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program 401(k) plan; paid vacation and holidays; paid leaves; and health benefits including medical prescription drug dental and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an at-will position and the Company reserves the right to modify base pay(as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.
Date Posted
25-Aug-2025Closing Date
28-Sep-2025Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and furtherance of that mission we welcome and consider applications from all qualified candidates regardless of their protected characteristics. If you have a disability or special need that requires accommodation please complete the corresponding section in the application form.
Required Experience:
Senior IC
Employment Type
Full-Time
