We are looking to support our rapidly growing team as soon as possible:

PhD position in Molecular Head and Neck Oncology (f/m/x)

TV-L: 231 h/week (60%) limited for 3 years according to WissZeitVG (Third-party funded project) Your salary will be based on TV-L TV-L: 231 h/week (60%) limited for 3 years according to WissZeitVG (Third-party funded project) Your salary will be based on TV-L

Your tasks

• In vitro and in vivo experiments on previously establishedpreclinical SDC models
• Establishment of a library of additional SDC cell lines andpatient-derived xenografts reflecting biologically relevantalterations
• Performance of well-established assays in our laboratory (e.g. in vitro drug assays in vivo drug efficacy experiments vectorbasedgene editing western blot PCR preparation of samplesfor genomic and transcriptomic sequencing analyses)

Your profile

• Excellent MSc degree in biology biotechnology or a relatedfield
• Strong interest in translational research in head and neckoncology
• Expertise in the following fields: Cell culture vector-based geneediting western blot in vivo mouse work ideally bioinformaticbasic skills
• Applicants should be highly motivated independent and havestrong communication skills

Our offer

• Everything but ordinary: You can expect a secure job in a challenging innovative environment including company pension schemes and regular working hours without business trips.
• Work-life balance: Whether full-time or part-time with or without children with numerous support options we will find the right path together.
• Team spirit in R(h)ine culture: You will be warmly welcomed by an interdisciplinary team that values mutual respect and helpfulness.
• Strong perspectives: We offer extensive training opportunities so you can continuously grow and set new goals.

Your future with us

We are one of the leading university hospitals in Germany and network research teaching and health care at the highest level. Thats why many things are a lot bigger for us: the spectrum of exciting development opportunities. The limitless openness with which specialists from all over the world work together here. Or our commitment as an employer to support all employees as best we can in reconciling their job with their goals and life situations.

This is the University Hospital of Cologne: Everything but ordinary.

Your future in detail

We are one of the largest and oldest universities in Europe and one of themost important employers in our region. Our broad range of subjects thedynamic development of our main research areas and our central locationin Cologne make us attractive to students and researchers from around theworld. We offer a wide range of career opportunities in science technologyand administration.

As part of the at the University Hospital of Cologne a PhD position in the area of cancercell biology is immediately available.
The research fellow will be supervised by Dr. Marcel Mayer and Prof. Peter Klumann and will be embedded in the group for MolecularHead and Neck Oncology (Head: Prof. Dr. Julie George). The overall aimof our research is to study and elucidate the biological processes of cancer
and investigating the molecular adaptation of cancer to therapeuticresponses in head and neck cancer. Among head and neck cancerssalivary gland carcinomas are a heterogenous group of malignant tumorsof the major and minor salivary glands. The clinically and biologically most
aggressive entity is salivary duct carcinoma (SDC). Although targetedtherapies for SDC are available their efficacy is low as knowledge aboutthe relevant signaling pathways in this tumor is extrapolated from morefrequent tumors. Therefore this project focuses on better understandingsignaling of the already available pathways and finding new targetablealterations in SDC in order to ultimately translate these findings into clinics.

Applications from female candidates are expressly welcome and will be given priority in the event of equal suitability competence and professional performance. People with disabilities are welcome to apply and will be treated preferentially in the event of equal suitability and qualification.

Contact

Petra Salewski
Tel: 49 2 Universittsklinikum Kln AR
Geschftsbereich Personal
Kerpener Str. 62
50937 Kln

Application deadline:17.08.2025

Job-ID: fcubzttg

We look forward to receiving your application and getting to know you!