Senior Scientist, Protein Purification
Senior Scientist, Protein Purification
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$ 90900 - 151500
1 Vacancy
Job Description
Role Summary
The Senior Scientist will be responsible for the process development work for a range of vaccine antigen modalities with a focus on subunit proteins. Key responsibilities include designing and executing experiments in membrane filtration and column chromatography to purify diverse proteins testing scale-up ensuring the manufacturability of the process and technology transfer. The role entails summarizing and evaluating study results as well as developing and testing new hypotheses to enhance our fundamental understanding of recovery and purification processes. It is essential that the Senior Scientist possesses strong scientific expertise in protein purification. Additionally the role involves performing analysis and characterization of isolated macromolecules using a variety of bioanalytical methodologies.
What You Will Achieve
In this role you will:
Develop optimize and scale-up recovery/purification processes for isolation of proteins.
Collaborate with colleagues within Vaccine Research and Development organization including Bioprocess Fermentation Analytical and Formulation Development groups.
Present problems and propose solutions in discussions with group members.
Plan and prioritize related recovery / purification activities.
Independently analyze interpret and provide conclusion and present experimental data.
Keep abreast of scientific/ technological development by participating in scientific meetings/ seminars and through regular scientific review. Utilize new technologies and establish those technologies to improve purification / recovery capabilities of process development group.
Qualifications
Must Have
Ph.D. and 0 - 2 years postdoctoral experience in industrial or academic setting
Proficiency with FPLC membrane filtration and relevant scientific software (eg. Unicorn)
Extensive laboratory research experience in protein purification and characterization
Strong understanding of protein chemistry and protein analytics
Experience with in-process analytical techniques
Ability to work independently and collaboratively in a team environment
Excellent oral and written communication skills
Nice to Have
Proficiency in process development
Experience in transferring biologics processes to pilot plants or manufacturing organizations
Solid understanding of data acquisition and control systems in bioprocess environments
Strong problem-solving skills and the ability to troubleshoot complex scientific challenges
Strong organizational skills and the ability to work on multiple projects simultaneously
Excellent interpersonal skills and the ability to work effectively with cross-functional teams
Other Job Details
Relocation support available
Work Location Assignment:On Premise
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care providers name address and the type of payments or other value received generally for public disclosure. Subject to further legal review and statutory or regulatory clarification which Pfizer intends to pursue reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse your name address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race color religion sex sexual orientation age gender identity or gender expression national origin disability or veteran status. Pfizer also complies with all applicable national state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Required Experience:
Senior IC
Employment Type
Full-Time
