Senior Scientist, I
Senior Scientist, I
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Salary Not Disclosed
1 Vacancy
Job Description
The Quantitative Translational & ADME Sciences (QTAS) team in Worcester MA is seeking a motivated and independent Senior Scientist to support pre-clinical bioanalytical studies in a non-regulated environment. This role focuses on understanding large molecule therapeutics pharmacokinetics and immunogenicity in safety and efficacy studies.
The primary responsibilities of a Senior Scientist include developing and executing bioanalytical strategies to support PK PD and TK studies using ligand binding assay platforms. This lab-based role emphasizes bioanalytical (PK and ADA) assay design planning and data interpretation to support oncology immunology and neuroscience portfolios.
The ideal candidate will have a strong background in immunology biochemistry and/or pharmacology or related fields. The candidate is expected to mentor and train bench scientists and provide scientific reasoning behind bioanalytical assay design and data interpretation.
This position is onsite and located at the AbbVie Bioresearch Center in Worcester MA.
Duties & Responsibilities:
- Design and execute pre-clinical (rodent NHP) bioanalytical studies using newly developed or existing bioanalytical protocols using immunoassays e.g. MSD.
- Effectively and clearly communicate assay plans timelines results and data interpretations with study teams and QTAS stakeholders.
- Serve as a scientific and technical consultant across teams.
- Train and mentor junior scientists.
- Archive data in ELN and LIMS systems.
- Write and update experimental protocols and procedures.
- Initiate design interpret and troubleshoot operational assays independently and efficiently.
Qualifications :
- Bachelors degree in biochemistry chemistry or pharmacology with 8 years industry experience; MS with 5 years of industry experience or a PhD with 0 years experience
- Previous experience conducting DMPK studies PK/PD/TK bioanalysis on antibodies bi/multi-specifics and/or ADCs including data interpretation is required.
- Highly motivated reliable and independent contributor with attention to detail and problem-solving skills.
- Required experience with assay development and troubleshooting using ligand binding workflows (ELISA MSD) is a must.
- Excellent written and verbal communication skills.
- Proficiency with computers and data analysis software including LIMS systems.
- Ability to design summarize communicate and interpret bioanalytical results.
- Creative leader and collaborative team player able to work effectively in a highly matrixed environment.
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:
No
Employment Type :
Full-time
Employment Type
Full-time
