Sr. Scientist II, Brain Transport Biology
Sr. Scientist II, Brain Transport Biology
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Job Description
The Discovery Neuroscience In Vivo Pharmacology group in Cambridge Massachusetts is seeking a highly skilled and self-motivated scientist to join a dynamic team supporting target identification validation and drug transport facilitation over brain barriers. The ideal candidate will also have people and project management experience and has experience making tangible contributions to the discovery pipeline.
Key Responsibilities:
- Responsible for design and implementation of in vivo testing of multispecific biologics small molecules and siRNAs to support projects in the areas of Alzheimers and Parkinsons disease
- Serve as an in vivo representative in cross-functional teams with Discovery Biotherapeutics DMPK and Development Sciences colleagues providing project updates analysis and strategic advice
- Collaborate with colleagues at various AbbVie and external sites
- Serve as the project lead responsible for coordinating activities and transitions from Hit Generation through Candidate Nomination
- Identify and solve technical problems independently implement new assays and workflows conceive and implement innovative research ideas
- Supervise junior scientists providing scientific and technical leadership in the design and execution of in vivo and ex vivo efficacy assessments and be accountable for the effective performance of the team
- Ensure consistency and quality of technical reports
- Present original work internally across departments and at internal and external scientific conferences; may author or co-author peer-reviewed scientific papers or patents
Qualifications :
Minimum Qualifications:
- Bachelors Degree or equivalent education and typically 12 years of experience Masters Degree or equivalent education and typically 10 years of experience PhD and typically 4 years of experience.
- Background in receptor and / or transporter biology
- Background in brain barriers biology
- Proven track record of working in multidisciplinary in vivo pharmacology teams
- Experience with in vivo models of neurodegeneration particularly with models of Alzheimers and Parkinsons Disease
- Proven track record in characterizing complex biotherapeutics in vivo (biologics small molecules siRNA)
- Experience managing direct reports including providing performance evaluations and development opportunities
- Excellent organizational skills and the ability to manage multiple projects simultaneously
- Demonstrated ability to collaborate effectively in a dynamic cross-functional matrix environment
- Candidate must be a goal-oriented team player with excellent verbal and written communication skills and strong can-do attitude
Preferred Qualifications:
- Prior project and team leadership in the pharmaceutical / biotech industry
- Experience in managing external collaborations
- Experience with ex vivo readouts including immunohistochemistry and biochemistry (ELISA WB)
- Experience with image analysis
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
This job is eligible to participate in our long-term incentive programs
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:
No
Employment Type :
Full-time
Employment Type
Full-time
