Scientist Protein Engineering Display Technologies
Scientist Protein Engineering Display Technologies
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$ 122830 - 148800
1 Vacancy
Job Description
Working with Us
Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here uniquely interesting work happens every day in every department. From optimizing a production line to the latest breakthroughs in cell therapy this is work that transforms the lives of patients and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope alongside high-achieving teams. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits services and programs that provide our employees with the resources to pursue their goals both at work and in their personal lives. Read more: Summary
We are seeking an enthusiastic creative and versatile Scientist to join our collaborative Protein Engineering team Engineering team in Redwood City/Brisbane (CA) to discover and engineer innovative biotherapeutic candidates and drive technological innovation. Our group acts on new ideas in the laboratory and thrives on the design-build-test cycle. You will solve complex protein engineering problems develop new skills and use them to implement robust platforms for protein therapeutic optimization. You will collaborate with talented colleagues across biotherapeutics and multiple therapeutic areas and further support AI/ML workflows. You will present at internal and external meetings contribute to therapeutic pipeline projects publications and patents. Responsibilities include library creation selection-based assays using protein display library technologies binder engineering for antibody-target interactions cross-function and cross-site collaboration.
Responsibilities
Drive efforts to engineer antibodies multispecifics and alternative biologics formats for optimal therapeutic performance
Selections on yeast display libraries routine operation and maintenance of a sorter and analyzer
Library design library construction NGS
Collaborate with AI/ML scientists for sequence and library design and support design-build-test cycles.
Independently perform routine molecular biology techniques DNA assembly and cloning design expression constructs for external synthesis and coordinate construct and library orders with CROs
Analyze library NGS data using no-code or low-code bioinformatics platforms
Independently perform complex experiments troubleshoot expertly analyze and interpret experimental results with strong attention to detail and documentation practices
Present results internally and externally attend industry conferences
Accomplish goals under project team timelines
Basic Qualifications
Bachelors Degree with 5 years of academic or industry experience
or
Masters Degree with 3 years of academic or industry experience or
or
PhD in Biochemistry Bioengineering Molecular Biology or related fields with 0-2 years of academic or industry experience
Preferred Qualifications
PhD in Biochemistry Bioengineering Molecular Biology or related fields with 0-2 years of relevant post-graduate or biotech/biopharma industry experience
Experience with molecular and microbiology techniques underlying yeast display work
Demonstrated experience in yeast display antibody/protein library construction sorting analytical binding etc.
Experience in antibody or protein engineering including but not limited to affinity maturation deep mutational scanning species cross-reactivity liability correction biophysical/physiochemical property remediation etc.
Flow cytometry and FACS experience is required
Experience in biotherapeutic lead discovery and optimization is desirable
Demonstrated experience in working in a cross-functional organization
Fundamental understanding of proteins antibodies and structure-function relationships required. Familiarity with protein structure analysis (Pymol Chimera MOE).
DNA and RNA purification cloning PCR Sanger sequencing NGS library preparation
Familiarity with protein-protein interaction techniques and kinetics (BLI SPR on-cell binding)
Bioinformatics or data science experience is desirable (bash Python or R)
Proficiency with Microsoft Office suite FlowJo Prism DNA cloning software
Excellent written and oral communication skills
The starting compensation for this job is a range from $122830 - $148800 plus incentive cash and stock opportunities (based on eligibility).
The starting pay rate takes into account characteristics of the job such as required skills and where the job is performed. Final individual compensation will be decided based on demonstrated experience.
Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits please visit our BMS Careers Site.
Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical pharmacy dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability life insurance supplemental health insurance business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays Global Shutdown days between Christmas and New Years holiday up to 120 hours of paid vacation up to two (2) paid days to volunteer sick time off and summer hours flexibility. Parental caregiver bereavement and military leave. Family care services such as adoption and surrogacy reimbursement fertility/infertility benefits support for traveling mothers and child elder and pet care resources. Other perks like tuition reimbursement and a recognition program.
If you come across a role that intrigues you but doesnt perfectly line up with your resume we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Uniquely Interesting Work Life-changing Careers
With a single vision as inspiring as Transforming patients lives through science every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture promoting global participation in clinical trials while our shared values of passion innovation urgency accountability inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol
BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential site-by-design field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles onsite presence is considered an essential job function and is critical to collaboration innovation productivity and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application or in any part of the recruitment process direct your inquiries to . Visit to access our complete Equal Employment Opportunity statement.
BMS cares about your well-being and the well-being of our staff customers patients and communities. As a result the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.
BMS will consider for employment qualified applicants with arrest and conviction records pursuant to applicable laws in your area.
If you live in or expect to work from Los Angeles County if hired for this position please visit this page for important additional information: data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
Employment Type
Full-Time
