Postdoctoral Associate - Xiao Wang Lab
Postdoctoral Associate - Xiao Wang Lab
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Job Description
General information
Description & Requirements
The Xiao Wang group at the Broad Institute of MIT and Harvard is seeking an energetic and motivated Postdoctoral Associate to engage with and collaborate within the lab and across different groups at the Broad. Our research program focuses on developing and applying state-of-the-art chemical and genomic analysis tools to chart cellular RNAs from birth to death and understand how the RNA life cycle is shaped and regulated in time and space to serve biological functions with an emphasis on the central nervous system. In parallel we aim to translate our understanding of RNA-centered gene regulation principles to design and engineer next-generation RNA drugs by expanding the alphabet structure and topology of synthetic RNAs to enhance their translation efficiency stability and tunability.
This role will require an in-office work capacity with the expectation to be in the office five days a week. The ideal candidate will have excellent oral and written communication skills interpersonal skills and the ability to collaborate across lab and administrative operations.
RESPONSIBILITIES
- Design characterization and engineering of RNA: e.g. in situ hybridization microarray gel electrophoresis HPLC SELEX NGS and single-cell RNA sequencing; RNA structure RNA modification/editing RNA localization RNA-protein complexes non-coding RNAs synthetic RNAs etc.
- Scientific investigation in neuroscience or other biological systems at the molecular and cellular levels
- Develop spatial omics methods using a hybrid of sequencing and imaging approaches
QUALIFICATIONS
- PhD in physical/biological science neuroscience bioengineering or related disciplines
- Experience with one or more domains: (a) animal handling in vivo studies stereotactic surgery; (b) pathological studies with human patient samples; (c) general tissue culture or organoid culture; (d) neuroscience research such as primary neuronal culture optogenetics and electrophysiology; (e) viral vector preparation such as AAV and lentivirus; (f) synthetic and analytical approaches to chemical and molecular biology such as nucleic acid chemistry organic synthesis and microscopy
- Experience working in a variety of lab spaces such as chemical benches tissue culture rooms microscope rooms and animal facilities
- Ability to multi-task and prioritize work
- Strong attention to detail and accuracy
- Ability to work both independently and as part of a team
Required Experience:
IC
Employment Type
Full Time
