Senior Principal Scientist, Attribute Sciences Biophysical Characterization, Analytical Operations
Senior Principal Scientist, Attribute Sciences Biophysical Characterization, Analytical Operations
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$ 205615 - 266090
1 Vacancy
Job Description
Were here for one reason and one reason only to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. Weve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But were not finished yet.
Join Kite as we make even bigger advances in cancer therapies and help shape where our business and medical science goes next.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future you are the key driver in evolving our culture and creating an environment where every employee feels included developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows.
Job Description
Gileads mission is to discover develop and deliver therapies that will improve the lives of patients with life-threatening illnesses
worldwide.
Reporting to Senior Director Attribute Sciences the Senior Principal Scientist Attribute Sciences Biophysical Characterization Analytical Operations will be responsible for leading a multi-disciplinary team that develops and utilizes state-of-the-art biophysical tools to assess product quality attributes that help guide process development and product knowledge of viral vector-based gene delivery platforms and T cell therapies.
In this role the ideal candidate will lead the strategy for development of advanced biophysical analytics capabilities in Analytical Development primarily Mass Spectrometry and extending to other technologies including Dynamic Light Scattering and Analytical Ultracentrifugation among others to understand the physical and chemical properties of vector and T cells. To be successful in this role the ideal candidate must have extensive expertise in biophysical technologies to support process development strategic thinking business acumen as well as excellent leadership skills.
Responsibilities include (but are not limited to):
Guide the development strategy for the use of mass spectrometry techniques used to assess viral vector and cell therapy final product attributes
Develop capabilities for in-house biophysical characterization of viral vectors (e.g. Dynamic Light Scattering Sedimentation-Velocity Analytical Ultracentrifugation Nanoparticle Tracking Analysis) to enhance viral vector product understanding.
Supervise and develop scientists/analysts within Attributes Sciences
Develop a high functioning team that is integrated in AD and cross-functionally to support business needs
Support team members hold them accountable for performance coach/mentor as well as provide performance reviews of team members
Enhance team capabilities to promote a diverse and complimentary analytical skill set to further process and product understanding
Work collaboratively with Cell and Vector Attribute Sciences teams to inform product characterization and product knowledge strategies to advance pipeline programs
Stay current with analytical technical platforms cell and gene therapy industry best practices as well as cutting edge innovations to support the development of cell therapy products
Qualifications
Ph.D. in Biochemistry Physical Chemistry Molecular Biology or related discipline with 8 years of industry experience or M.S. degree (M.S.) with 10 years of industry experience
Advanced knowledge of cell biology cancer biology and/or immunology preferred
Extensive hands-on experience on the use of mass spectrometry for proteomics applications
Experience performing biophysical analysis (e.g. Dynamic Light Scattering Sedimentation-Velocity Analytical Ultracentrifugation Nanoparticle Tracking Analysis) in scientific or technical environments to drive business solutions
Proficiency in mass spectrometry and proteomics data analysis tools and methodologies including interpretation and statistical analysis on large datasets
Strong scientific writing and presentation skills
Ability to think critically and demonstrate troubleshooting and problem-solving skills
Highly collaborative with excellent interpersonal verbal and written communication skills
Self-motivated detail-oriented and willing to accept temporary responsibilities outside of initial job description
Comfortable in a dynamic fast-paced environment with minimal direction
Demonstratedleadership abilityin pharmaceutical manufacturing of biotechnology products cell therapy productsanalyticalmethod development and process development
Agile mindset and ability to adjust workload based upon changing priorities
Ability towork in lead andfostercross-functionalcollaborativeteams
Experiencesupporting developing and mentoring staff and creatinginclusive high-performing teams
Ability to foster an organization that demonstrates integrity accountability teamwork andexcellence
People Leader Accountabilities:
Create Inclusion - knowing the business value of diverse teams modeling inclusion and embedding the value of diversity in the
way they manage their teams.
Develop Talent - understand the skills experience aspirations and potential of their employees and coach them on current
performance and future potential. They ensure employees are receiving the feedback and insight needed to grow develop and
realize their purpose.
Empower Teams - connect the team to the organization by aligning goals purpose and organizational objectives and holding
them to account. They provide the support needed to remove barriers and connect their team to the broader ecosystem.
For additional benefits information visit:
Kite Pharma is committed to providing equal employment opportunities to all employees and applicants for employment and is dedicated to fostering an inclusive work environment comprised of diverse perspectives backgrounds and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race color religion national origin sex age sexual orientation physical or mental disabilitygenetic information or characteristic gender identity and expression veteran status or other non-job related characteristics or other prohibited grounds specified in applicable federal state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973 the Vietnam Era Veterans Readjustment Act of 1974 and Title I of the Americans with Disabilities Act of 1990 applicants who require accommodation in the job application process may contact for assistance. NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT PAY TRANSPARENCY NONDISCRIMINATION PROVISION Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Please apply via the Internal Career Opportunities portal in Workday.
Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune systems ability to recognize and kill tumors. Kite is based in Santa Monica CA. For more information on Kite please visit . Sign up to follow @KitePharma on Twitter at jobs in the United States:
For more information about equal employment opportunity protections please view theKnow Your Rights poster.
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT
Kite Pharma provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.For Current Kite Pharma Employees and Contractors:
Required Experience:
Staff IC
Employment Type
Full-Time
