Postdoctoral Scientist - Mendoza Lab
Postdoctoral Scientist - Mendoza Lab
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1 Vacancy
Job Description
Current HHMI Employees click here to apply via your Workday account.
About the Mendoza Lab:
The Mendoza Lab focuses on structure-based protein engineering to understand cellular signaling pathways in human immunity with particular emphasis on cancer and viral immunity. Our goal is to develop protein-based therapeutics by combining biochemical structural and computational approaches.
Learn more about the lab: the Role:
We are seeking a highly motivated Postdoctoral Scientist to join our dynamic team. Candidates should have a strong interest in protein biochemistry membrane proteins and structural determination methods such as X-ray crystallography or cryo-EM (training available).
What Youll Do:
Leverage proprietary platforms to:
Screen cytokine signaling pathways and identify druggable targets
Apply structure-based engineering to design and develop protein-based therapeutics
Collaborate across multidisciplinary teams both internally and with external partners
Integrate computational and structural data to guide rational protein engineering
Perform molecular biology and protein biochemistry experiments
Conduct structural biology studies and analyze protein structures
Design and execute cell-based assays for functional validation
Analyze next-generation sequencing data to inform experimental decisions
Coordinate with collaborators on the design and analysis of in vivo studies
Lab Resources & Equipment:
FPLCs with a fluorimeter
Incubators for mammalian bacterial and yeast culture
Thermocyclers qPCR instrumentation
Ion Torrent NGS system (supports RNA-seq and libraries up to 500bp)
4-laser 11-color flow cytometer
Robotics for high-throughput crystallography
Nanotemper Monolith MST instrument for affinity measurements
Access to cryo-EM facilities at the University of Chicago
What We Provide:
A supportive mentorship-focused lab culture committed to your scientific and career development
Access to the University of Chicago workshops and classes on scientific communication grant writing and job preparation
Opportunities to train in cryo-EM through internal and collaborative efforts
Funding consideration for scientific conferences and external training programs
Full access to HHMIs on-demand training courses and live seminars led by expert instructors
What You Bring:
Ph.D. and/or M.D./Ph.D. in structural biology biochemistry biophysics molecular biology or a related field
Less than two years of postdoctoral research experience
Experience with protein production cloning and cell-based assays
Excellent communication skills self-motivation and the ability to multitask in a collaborative environment
Interest or experience in computational biology and AI/machine learning (highly preferred)
Physical Requirements
Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet).
Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.
Please Note:
This job description sets forth the jobs principal duties responsibilities and requirements; it should not be construed as an exhaustive statement however. Unless they begin with the word may the Essential Duties and Responsibilities described above are essential functions of the job as defined by the Americans with Disabilities Act.
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Compensation and Benefits
Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission including competitive pay exceptional health benefits retirement plans time off and a range of recognition and wellness programs. Visit our Benefits at HHMI site to learn more.
Compensation Range
$70000.00 (minimum) - $80500.00 (midpoint) - $91000.00 (maximum)Pay Type:
AnnualHHMIs salary structure is developed based on relevant job market data. HHMI considers a candidates education previous experiences knowledge skills and abilities as well as internal consistency when making job offers. Typically a new hire for this position in this location is compensated between the minimum and the midpoint of the salary range.
HHMI is an Equal Opportunity Employer
We use E-Verify to confirm the identity and employment eligibility of all new hires.
Employment Type
Full-Time
