Principal Research Scientist I, Peptide Medicinal Chemist
Principal Research Scientist I, Peptide Medicinal Chemist
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1 Vacancy
Job Description
Small Molecular Therapeutics and Platform Technologies (SMTPT) within Discovery Research seeks an accomplished scientist to lead a team of medicinal chemists within the Global Medicinal Chemistry (GMEC) organization. GMEC is committed to delivering first and best-in-class small molecules in conventional and unconventional drug-like space with the potential to improve human health. The Principal Research Scientist I/Senior Scientist II will lead a team of chemists designing and synthesizing peptides (or other small molecule modalities) aimed at identifying and advancing promising low dose leads (responsibility for lead generation through candidate nomination).
She/He/They will be responsible for managing a diverse team of scientists who design and synthesize peptide drug candidates for novel targets throughout AbbVies drug discovery pipeline. She/He/They may serve as Chemistry Lead for some of these efforts. She/He/They will also be a strong synthetic chemist who has demonstrated high productivity in synthesizing complex organic molecules including peptides. She/He/They and team will develop novel medicinal chemistry strategies and execute multiparametric optimization(s) of drug candidate properties in a highly collaborative environment aimed at accelerating the delivery of a sustainable pipeline of first in class/breakthrough peptide drug candidates with transformative potential.
The candidate will have experience with strategic planning and leadership of medicinal chemistry teams as well as working with cross-functional and matrixed teams within the AbbVie therapeutic areas. The candidate will have a strong expertise in modern medicinal chemistry including an appreciation of modern computational and experimental tools multidisciplinary inputs and synthetic technologies needed to develop low dose peptide drug candidates. The ideal candidate will be able to lead by influence in a matrix environment and maintain a productive collaborative and inclusive environment. Strong communication skills are essential as the candidate must be able to tailor interactions with technical teams and represent the medicinal chemistry advances to AbbVie leadership.
Key responsibilities:
- Drive performance by leading team members in the design and synthesis of low dose peptide drug candidates and the development of stage-appropriate progression funnels for their identification
- Maintain a high level of productivity in the laboratory setting
- As programs advance work with key stakeholders in the Development sciences core team to address and reduce risks in collaboration to drive towards candidate nomination
- Manage chemistry team activities and professional development of a team of scientists through effective mentoring guidance and supervision
- Advance scientific expertise within the function and collaborate with cross-disciplinary teams to advance drug candidates from research to development
- Ensure the quality and effectiveness of key project results through sound medicinal chemistry design early risk assessments and implementation of fallback strategies
- Provide expert advice and share knowledge with direct reports peers and senior management
- Provide guidance to develop both the skills and the careers of direct reports.
- Train and mentor functional colleagues and assess current and emerging business challenges to achieve functional goals
- Identify and integrate emerging scientific trends from internal and external sources into functional objectives
- Present program updates and research strategies to functional and non-functional leaders as well as potential and existing partners
- Maintain awareness of emerging literature and science in the field and author scientific disclosures/publications
- Maintain scientific presence outside AbbVie with appropriate publication and conference abstract submission highlighting innovative medicinal chemistry learnings
Significant Work Activities - Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8-hour day)
Qualifications :
- BS or equivalent education and extensive Typically 14 years of experience; MS or equivalent education with typically 12 years of experience; PhD with typically 6 years of experience in area or scientific area of discipline.
- Proven track record of productivity in the laboratory setting
- Experience in peptide synthesis
- Extensive knowledge and experience in modern medicinal chemistry
- Highly organized and self-directed experience leading medicinal chemistry teams
- Excellent written and verbal communication is required as well as critical evaluation and data-driven decision making
- Highly collaborative team-oriented and considerate of the needs of others
- Strong interpersonal skills and ability to collaborate with diverse groups within the organization and external partners
- Proven chemistry team leadership and management abilities including experience mentoring guiding supervising and developing early career chemists
- Ability to create an inclusive environment where diverse ideas viewpoints and backgrounds are valued; willingness and ability to lead inclusively and demonstrate a commitment to listen and consider all points of view
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
This job is eligible to participate in our long-term incentive programs
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
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No
Employment Type :
Full-time
Employment Type
Full-time
