Senior Data Scientist, Mass Spectrometry, Science
Senior Data Scientist, Mass Spectrometry, Science
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$ 190000 - 285000
1 Vacancy
Job Description
The Chan Zuckerberg Initiative was founded by Priscilla Chan and Mark Zuckerberg in 2015 to help solve some of societys toughest challenges from eradicating disease and improving education to addressing the needs of our local communities. Our mission is to build a more inclusive just and healthy future for everyone.
The Team
CZI supports the science and technology that will make it possible to help scientists cure prevent or manage all diseases by the end of this century. While this may seem like an audacious goal in the last 100 years biomedical science has made tremendous strides in understanding biological systems advancing human health and treating disease.
Achieving our mission will only be possible if scientists are able to better understand human biology. To that end we have identified four grand challenges that will unlock the mysteries of the cell and how cells interact within systems paving the way for new discoveries that will change medicine in the decades that follow:
- Building an AI-based virtual cell model to predict and understand cellular behavior
- Developing state-of-the-art imaging systems to observe living cells in action
- Instrumenting tissues to better understand inflammation a key driver of many diseases
- Engineering and harnessing the immune system for early detection prevention and treatment of disease
The Opportunity
As a Senior Data Scientist youll lead the creation of groundbreaking datasets that power our scientific grand challenge to instrument tissues to understand inflammationa cutting-edge initiative to determine the role of inflammation in disease and the molecular mechanisms through which it acts. Working at the intersection of data science biology and AI your work will focus on mass spectrometry spanning proteomics metabolomics and mass spectrometry imaging data. You will define data needs format standards analysis approaches and quality metrics and build pipelines to ingest transform and validate data products that form the foundation of our experiments.
Our Data Ecosystem:
These efforts will form a part of and interoperate with CZIs larger data ecosystem. We are generating unprecedented scientific datasets that drive biological innovation:
- Billions of standardized cells of single-cell transcriptomic data with a focus on measuring genetic and environmental perturbations
- 10s of thousands of donor-matched DNA & RNA samples
- 10s PBs-scale static and dynamic imaging datasets
- 100s TBs-scale mass spectrometry datasets
- Diverse large multi-modal biological datasets that enable biological bridges across measurement types and facilitate multi-modal model training to define how cells act.
When analysis of a dataset is complete you will help publish it through public resources like CELLxGENE Discover and the CryoET Portal used by tens of thousands of scientists monthly to advance understanding of genetic variants disease risk drug toxicities and therapeutic discovery.
Your Impact
Youll collaborate with cross-functional teams to lead dataset definition ingestion transformation and delivery for AI modeling and experimental analysis. Success means delivering high-quality usable datasets that directly address modeling challenges and accelerate scientific progress. Join us in building the data foundation that will transform our understanding of human biology and move us along the path to curing preventing and managing all disease.
What Youll Do
- Contribute the tools required for a robust data ecosystem: build mass spec data ingestion pipelines select data formats standards and database schemas and write validation tools QC approaches and analysis pipelines.
- Collaborate with Platform Scientists ML engineers AI Researchers and Data Engineers to iteratively evaluate refine and grow datasets to improve our biological understanding of inflammation.
- Work closely with Platform Scientists to identify technical variables and devise approaches to harmonize data across generation sites to enable joint analysis.
- Discover and define new data generation opportunities and manage the delivery of those data products to our scientific teams.
What Youll Bring
- 10 years of experience with large scale mass spectrometry (proteomics metabolomics mass spectrometry imaging).
- Demonstrated ability to deliver multiple large biological data products.
- Experience with big data: extraction transport loading databases standardization validation QC and analysis.
- Experience with processing and orchestration pipelines such as Argo Workflows Databricks
- Strong fundamentals in statistical reasoning and machine learning.
- Experience with biological data analysis and QC best practices
- Excellent written and verbal communication skills.
- Enthusiasm to ramp up on technologies and learn new domains.
- Experience working in a multidisciplinary environment (scientific platforms engineering product AI Research).
Compensation
The Redwood City CA base pay range for this role is $190000.00 - $285000.00. New hires are typically hired into the lower portion of the range enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience as evaluated throughout the interview process.
Pay ranges outside Redwood City are adjusted based on cost of labor in each respective geographical market. Your recruiter can share more about the specific pay range for your location during the hiring process.
Benefits for the Whole You
Were thankful to have an incredible team behind our work. To honor their commitment we offer a wide range of benefits to support the people who make all we do possible.
- CZI provides a generous employer match on employee 401(k) contributions to support planning for the future.
- Annual benefit for employees that can be used most meaningfully for them and their families such as housing student loan repayment childcare commuter costs or other life needs.
- CZI Life of Service Gifts are awarded to employees to live the mission and support the causes closest to them.
- Paid time off to volunteer at an organization of your choice.
- Funding for select family-forming benefits.
- Relocation support for employees who need assistance moving to the Bay Area
- And more!
If youre interested in a role but your previous experience doesnt perfectly align with each qualification in the job description we still encourage you to apply as you may be the perfect fit for this or another role.
Explore ourwork modesbenefits andinterview processat
Required Experience:
Senior IC
Employment Type
Full Time
