Scientist, Process Development - Medicines for All Institute
Scientist, Process Development - Medicines for All Institute
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Job Description
All full-time university staff are eligible for VCUs robust benefits package that includes: comprehensive health benefits paid annual and holiday leave granted up front generous tuition benefit retirement planning and savings options tax-deferred annuity and cash match programs employee discounts well-being resources abundant opportunities for career development and advancement and more. Learn more about VCUs benefits here.
- Conduct and thoroughly document literature reviews for target chemical transformations intermediates and APIs.
- Conceptualize practical synthetic strategies (route design / retrosynthesis) for target APIs and intermediates. Assess viability of prospective routes with a view to low-cost raw materials.
- Maintain strong technical literacy. Develop hypothesis-driven experimental process research efficiently screen many valid reaction conditions and identify trends for improved process development perform careful data-rich experiments that create a deep knowledge of the chemical system. Translate previous results into new experiments that will lead to lower costs and/or process improvements.
- Execute chemical reactions on screening (milligram to gram) and preparative (decagram to kilogram) scales in the context of process research (route scouting) and development (optimization).
- Leverage high-throughput experimentation equipment and software (including automation) to achieve efficient cycles of design-test-analyze and build M4ALL reaction databases.
- Deliver results in a high-pace and time-sensitive environment.
- Demonstrate robust data interpretation. Incorporate data-driven insights into reports and designs for chemical processes.
- Maintain a detailed accurate and up-to-date electronic lab notebook (ELN) to ensure robust knowledge management.
Project Management
- Demonstrate timely and proficient use of M4ALLs project management technology platforms to facilitate internal and external communications.
- Demonstrate project budget awareness and good stewardship in the purchase and use of consumables reagents solvents key starting materials and intermediates.
- Adhere to project timeline and deliverable commitments. Escalate risks and deviations to ensure client transparency.
Strategy Development & Execution
- Support the development of new technology platforms that accelerate drug substance development and differentiate M4ALLs technical offerings. (Advanced Chemistry Technology)
- Challenge the status quo by continuously reviewing personal work processes and questioning traditional or established processes with the aim of constantly improving M4ALL operations and customer / collaborator experience.
Interdepartmental and External Communications
- Prepare clear accurate and concise written project updates and reports (pptx docx) representing your contributions. Contribute well-written high-quality scientific content for publication e.g. peer-reviewed articles trade journal articles white papers M4ALL social media. (Technical Writing)
- Orally present research updates and reports on findings in-person or virtually for internal consumption. Develop and deliver high quality oral presentations (posters group meetings) to internal scientific and non-scientific audiences. (Verbal / Oral Communications)
- Recognize signs of interpersonal or project misalignment. Attempt to resolve misunderstandings with support of line manager if needed. Seek clarity on responsibilities and expectations to minimize misalignments or misunderstandings. (Conflict Resolution)
- Contribute to variety of scientific materials such as paper studies publications manuscripts (as above) and other documents supporting ongoing and future work in the labs (e.g. SOPs Work Instructions Hazard Assessments etc.)
Team & Infrastructure Development
- Support onboarding new Scientists Technicians and Postdocs as members of buddy network to ease their transition into the M4ALL team.
- Develop a thorough understanding of M4ALL tech (IT) and infrastructure for critical unit operations how to use it. (Leverage and Grow Technology Prowess)
Mindset
- Demonstrate resource stewardship accountability commitment to quality work appreciation of your works criticality to the M4ALL mission (Ownership)
- Show willingness to compromise on pathways to a common goal putting clients priorities first (Flexibility)
- Show willingness to change course in the face of changing business needs and opportunities. Be resilient in face of change. (Adaptability)
- Listen to stakeholders (internal and external) and address needs and concerns. Deliver on service commitments: Maintain supportive relationships with stakeholders. (Service Excellence)
Required Education & Technical Abilities
- PhD in organic organometallic or inorganic chemistry. Individuals with significant years experience and training equivalent to a PhD will be considered.
- Minimum of 3 years of relevant industrial experience
- Demonstrated ability to lead project workstreams deliver technical results and collaborate effectively with clients
- Ability to publish research findings in high impact scientific journals. Preference will be given to candidates who demonstrate a proven track record of publications.
- Proven expertise in industrial process research process development scale-up and tech transfer
- Strong understanding of and experience with all analytical methods relevant to synthetic organic chemistry (NMR HPLC MS IR UV etc).
Required Interpersonal Skills & Individual Aptitude
- Full professional proficiency of the English language (speaking reading and writing)
- Comfort and confidence to give presentations...
- Accountability and collaborative mindset...
- Innovative and creative problem solving...
- Open-mindedness and commitment to valuing diversity...
- Energy and passion to thrive in a start-up environment...
- Commitment to aligning and adherence to M4ALLs core values and purpose.
** Please note applicants must be authorized to work in the United States without the need for current or future visa or permanent residence sponsorship. Sponsorship is not available for this position.
Reporting Structure
This role reports to the Associate Director Process Development and embodies everyday leadership with an expectation to lead through actions discussions decisions and interactions. As a role model within the organization you will influence others by consistently demonstrating the values and behaviors that drive our mission forward.
Work Environment and Location
100% onsite at the VA BioTech Park located in Richmond Virginia. Additionally this position may require occasional domestic and international travel. Candidates should be comfortable with and prepared for infrequent travel as needed. Since M4ALLs inception in 2017 we have received significant financial support from a diverse portfolio of major donors. This position is grant-funded with continued employment contingent upon ongoing funding.
Employment Type
Full Time
