Senior Research Scientist II / Principal Research Scientist I, Biologics Analytical R&D
Senior Research Scientist II / Principal Research Scientist I, Biologics Analytical R&D
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Job Description
Group:
AbbVie Biologics Analytical Research & Development (Biologics Analytical R&D) is a global analytical sciences organization responsible for all CMC analytical activities related to the development of AbbVies pharmaceutical products. Our scope includes AbbVies diverse pipeline of innovative therapeutic biologic medicines and spans from the selection of Discovery candidate molecules through the transition of analytical methods and testing to commercial labs to support product launch. We are building a world-class team of scientists and leaders who will drive the advancement of industry-leading analytical capabilities and make meaningful contributions to advance AbbVies pipeline of innovative medicines. Careers in AbbVie Biologics Analytical R&D provide unique opportunities to work with global and cross-functional teams to drive exceptional science and innovative product development strategies.
The biologics characterization group develops state-of-the-art analytical techniques for in-depth characterization of therapeutic proteins and other novel biologic molecules using mass spectrometry and other advanced analytical techniques. We are looking for diverse candidates with strong scientific and leadership experience to join the AbbVie Analytical R&D team and can offer exciting and rewarding career opportunities for these candidates.
Key Responsibilities
- Subject matter expert in establishing development of novel analytical methods to characterize peptides oligonucleotides ADCs and novel antibody therapeutics including HPLC LC-MS CD DLS SEC-MALS ELISA/SPR.
- Contribute to phase-appropriate buildout of analytical methods for extended characterization product release stability comparability and in-process analytics.
- Guide and support assay development from development optimization through validation.
- Serve as a key scientific and technical representative on cross-functional teams; collaborates and integrates scientific objectives associated with development of new/improved products or technology.
- Effectively function as an analytical scientist generating original technical ideas and research or development strategies.
- Make significant contributions to project team and deliver results in a team-oriented setting and will work across scientific disciplines to drive programs through critical milestones.
- Generate new scientific proposals and lead those efforts. Anticipate and critically evaluate scientific or regulatory advances or competitive threats and respond with appropriate new strategies.
- Author review lab notebook analytical report and analytical sections of regulatory filings. Primary author of publications presentations regulatory documents and/or primary inventor of patents. Present at leading scientific conferences.
- May mentor/supervise a team of one or more and guide and evaluate the performance of those individuals; is accountable for the effective performance of the team/individuals.
Qualifications :
- PhD with scientific discipline is preferred (e.g. Analytical Chemistry Biochemistry or Biology) with previous laboratory experience.
- Senior Scientist II: Bachelors Degree or equivalent education and typically 12 years of experience Masters Degree or equivalent education and typically 10 years of experience PhD and typically 4 years of experience.
- Principal Research Scientist I: BS or equivalent education and extensive Typically 14 years of experience; MS or equivalent education with typically 12 years of experience; PhD with typically 6 years of experience in area or scientific area of discipline.
- Well versed in analytical techniques including but not limited to HPLC LC-MS CD DLS SEC-MALS ELISA/SPR.
- Demonstrated experience with peptides and/or oligonucleotides method developments and optimization is strongly preferred
- Deep understanding and hands-on experience with biophysical-based and/or mass spectrometry-based higher order structures (HOS) characterizations strongly preferred
- Demonstrated experience of lab automation (Lynx Hamilton Tecan etc.) is a strong plus
- Practical understanding of fit-for-purpose and stage-appropriate method development risk assessment and control strategy in Analytical Development setup
- Demonstrate independent problem-solving ability in science and technical proficiency.
- Strong data and time organization/management skills coupled with strong interpersonal and effective communication skills for facilitating collaborations with a demonstrated ability to lead cross functional process development teams.
Additional Information :
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:
- This is an on-site opportunity.
- Leveling will be commensurate to experience.
- The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future. Salary: $121000- $230000
- We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
- This job is eligible to participate in our short-term incentive programs.
- This job is eligible to participate in our long-term incentive programs
Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
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No
Employment Type :
Full-time
Employment Type
Full-time
