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Postdoctoral Project Research Scientist

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Job Location drjobs

London - UK

Monthly Salary drjobs

Not Disclosed

drjobs

Salary Not Disclosed

Vacancy

1 Vacancy

Job Description

Salary for this Role:

From 45500 with benefits subject to skills and experience

Job Title:

Postdoctoral Project Research Scientist

Reports to:

Rashmi Priya

Closing Date:

30/Jun/2025 23.59 GMT

Job Description:

Postdoctoral Project Research Scientist

Details of the role: This is a full-time fixed term (two years) position on Crick terms and conditions of employment.

About us

The Francis Crick Institute is Europes largest biomedical research institute under one roof. Our world-class scientists and staff collaborate on vital research to help prevent diagnose and treat illnesses such as cancer heart disease infectious diseases and neurodegenerative conditions.

The Crick is a place for collaboration innovation and exploration across many disciplines. A space where the brightest minds can pursue big and bold ideas and discover answers to crucial scientific questions. We support them in a dynamic environment which fosters excellence with state-of-the-art infrastructure cutting-edge facilities and a creative and curious culture. Weve removed traditional boundaries of departments divisions and disciplines and instead have an open approach that supports every researcher. This gives us the freedom to take risks and carry out high-quality pioneering research. Creating a space for discovery without boundaries helps us to turn our science into benefits for human health and the economy.

About the role

We are seeking an experienced Postdoctoral Project Research Scientist to join our team. In this role you will both lead your own independent project(s) and contribute to the development of innovative tools and technologies that advance the labs research program. You will be part of a collaborative and diverse group dedicated to uncovering how a functional beating heart is formed during development. Your work will involve applying in-depth technical expertise in cutting-edge imaging technologies image analysis techniques and biophysical approaches. The specific goals and direction of the project(s) will be shaped in close consultation with the supervisor and tailored to your background and interests.

The heart is the first organ to form and function during embryonic development. A key step during vertebrate heart development is chamber maturation a poorly-understood morphogenetic process critical for heart function. During this process the myocardial wall of the ventricle and atrium transforms from a single-layered epithelium into a complex 3D topological meshwork architecture (Priya et al. 2021 Nature; bioRxiv2024.07.24.604962; bioRxiv 2025.03. 07.641942). How this topological complexity is achieved is unknown as are the underlying mechanisms that shape these crucial anatomical structures. In our lab we aim to unravel the underlying mechanical molecular and geometric interactions that transform a developing heart from a simple epithelium into a highly intricate functional organ. We combine the excellent tractability of zebrafish embryos with quantitative imaging transcriptomics biophysics genetics and predictive theoretical modelling to answer fundamental questions driving organ morphogenesis.

What you will be doing:

As aPPRS you will:

  • Develop and establish new tools and techniques advanced 4D live imaging of zebrafish hearts image analysis pipelines biophysical methods for measuring mechanical forces and gene-editing tools.
  • Conceptualize and lead research project(s)
  • Provide expert guidance and technical support to lab members fostering knowledge exchange and skill development.
  • Contribute to other projects on a collaborative basis both in the lab and with external collaborators.
  • Actively contribute to the development and publication of scientific manuscripts
  • Help cultivate a collaborative inclusive and intellectually stimulating lab environment.

About you

You will bring

  • PhD (or near completion) in cell biology developmental biology or biophysics.
  • Proven expertise in advanced confocal and light-sheet microscopy as shown by publications.
  • Strong expertise in quantitative image analysis techniques.
  • Excellent skills in molecular biology.
  • Experience in embryological techniques (zebrafish/fly/mouse) as well as gene editing methods.
  • Demonstrated ability to write scientific papers as shown by publications and/or preprints in relevant fields.

See the full job description here

See more about the team here

About Working at the Crick

Our values

Everyone who works at the Crick has a valuable role to play in advancing the Cricks mission and shaping our culture!

At the Francis Crick Institute we believe that diversity and inclusion are essential to driving innovation and scientific discovery. We are committed to creating a workplace where everyone feels valued respected and empowered to succeed regardless of their background identity or personal circumstances. We actively encourage applications from individuals of all genders ethnicities abilities and experiences. Weare aDisability Confident: Committedemployer andwant to ensure that everyone can apply and be part of our recruitment processes and sowellmake reasonable adjustments if you need them - just let us know when you apply. If you needassistancewith applying (i.e. would like to apply by phone or post)please email:

To find out more about life at the Crick clickhere.

What will you receive

At the Francis Crick Institute we value our team members and are proud to offer an extensive range of benefits to support their well-being and development:

Employment Type

Full-Time

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